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The objective of this prospective study was to investigate whether repeated consecutive general anesthesia in horses undergoing 2 different anesthetic protocols could lead to improved recovery scores. Six healthy female Standardbred horses (453 ± 57 kg; 6.5 ± 4.

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The aim of this retrospective clinical study was to compare the combinations of ketamine/diazepam (KD group) and tiletamine/zolazepam (TZ group) for the induction of general anaesthesia in horses undergoing elective surgery. The data from the clinical and the anaesthetic records of 138 horses from 2021 to 2023 were evaluated, and the horses were divided in two groups: KD ( = 60) and TZ ( = 72). The horses were premedicated with romifidine and methadone IV; anaesthesia was induced with ketamine/diazepam for the KD group and tiletamine/zolazepam for the TZ group and was maintained with isoflurane and a constant rate infusion of romifidine.

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Objective: To explore the influence of acepromazine on the cardiovascular effects of dobutamine in isoflurane-anaesthetised horses premedicated with romifidine.

Study Design: Prospective randomised clinical trial.

Animals: A total of 18 horses undergoing elective arthroscopy were enrolled, of which 12 horses requiring dobutamine were included.

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Pathogenic role of acyl coenzyme A binding protein (ACBP) in Cushing's syndrome.

Nat Metab

December 2024

Metabolomics and Cell Biology Platforms, UMS AMMICa, Gustave Roussy Institut, Villejuif, France.

Article Synopsis
  • Cushing's syndrome is linked to high levels of glucocorticoids and is associated with increased plasma levels of ACBP/DBI, which stimulates food intake and fat production.
  • Researchers explored multiple methods to inhibit ACBP/DBI in mice, including genetic modifications and antibody injections, to address Cushing's symptoms.
  • The findings suggest that targeting ACBP/DBI could be an effective strategy for treating Cushing's syndrome and its related complications like obesity and diabetes.
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Anesthesia in animals is a crucial requirement for conducting surgery, diagnostic imaging, and other procedures when the animal cannot be safely managed in a conscious state. The present study aimed to compare the impact of different anesthetic techniques on the electrocardiogram of hedgehogs. The animals were given three different anesthetic combinations: ketamine + xylazine, ketamine + diazepam, and ketamine + midazolam.

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