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Knosp and revised Knosp classifications predict non-functioning pituitary adenoma outcomes: a single tertiary center experience.
J Med Life
November 2024
Department of Endocrinology, Diabetology and Nutrition, Mohammed VI University Hospital, Medical School, Mohamed the First University, Oujda, Morocco.
Non-functioning pituitary adenomas (NFPAs) are hormonally inactive benign tumors, usually diagnosed as macro-adenoma. The aim of our research was to analyze the clinical and hormonal characteristics of NFPAs using Knosp and revised Knosp classifications. Furthermore, we aimed to assess the possibility of predicting surgical remission after surgery.
View Article and Find Full Text PDFThe role of elagolix in ovulation suppression during controlled ovarian stimulation: a retrospective cohort study.
F S Rep
December 2024
Department of Embryology, Newlife Fertility Centre, Mississauga, Ontario, Canada.
Objective: To compare in vitro fertilization treatment outcomes for the oral gonadotropin-releasing hormone (GnRH) antagonist elagolix (E) to the conventionally used injectable GnRH antagonist ganirelix (G) for achieving pituitary gonadotropin suppression during a controlled ovarian stimulation (COS) cycle.
Design: Retrospective cohort study.
Setting: Private university-affiliated fertility center.
Use of "enhanced contact endoscopy for pituitary surgery" in a collision sellar tumor (papillary craniopharyngioma + non-functional pituitary adenoma): Representative case illustration and two-dimensional operative video.
Surg Neurol Int
December 2024
Center for Skull Base and Minimally Invasive Neurosurgery, Hospital Angeles Pedregal, Centro de Especialidades Quirúrgicas, Mexico City, Mexico.
Background: Collision sellar tumors are rare disease entities. Less than 30 cases have been reported in the literature in the last 20 years. We present the case of one patient diagnosed with a collision sellar tumor and describe the use of Enhanced Contact Endoscopy for pituitary gland and tumoral identification not previously described in the literature.
View Article and Find Full Text PDFKisspeptin and Endometriosis-Is There a Link?
J Clin Med
December 2024
Department of Gynecological Endocrinology, Poznan University of Medical Sciences, 60-535 Poznan, Poland.
This article presents a narrative review that explores the potential link between kisspeptin-a key regulator of the hypothalamic-pituitary-gonadal axis-and the pathogenesis of endometriosis. Kisspeptin plays a significant role in regulating reproductive functions by modulating the release of gonadotropin-releasing hormone (GnRH), which in turn stimulates the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Recent studies suggest that kisspeptin may also impact peripheral reproductive tissues and influence inflammatory processes involved in the development of endometriosis.
View Article and Find Full Text PDF·Role of Cathepsin K in Bone Invasion of Pituitary Adenomas: A Dual Mechanism Involving Cell Proliferation and Osteoclastogenesis.
Cancer Lett
January 2025
Department of Endocrinology, The First Medical Center of Chinese PLA General Hospital, Beijing, China 100853. Electronic address:
This study aimed to investigate the regulation and underlying mechanism of Cathepsin K (CTSK) in bone-invasive pituitary adenomas (BIPAs). A total of 1437 patients with pituitary adenomas were included and followed up. RNA sequencing, immunohistochemistry, and qRT-PCR were used to analyze CTSK expression.
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