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Outcomes of total cystectomy with medical treatment in canine urothelial carcinoma of the bladder trigone.

Can Vet J

March 2025

Veterinary Medical Center (Takahashi, Motegi, Fujita, Hashimoto) and Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences (Kato, Nakagawa, Nishimura) and Laboratory of Veterinary Clinical Pathobiology, Graduate School of Agricultural and Life Sciences (Maeda), The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.

Objective: This study aimed to evaluate outcomes and complications in dogs with urothelial carcinoma (UC) of the bladder trigone treated with total cystectomy using uretero-prepuce/vagina/cutaneous anastomosis combined with medical treatment.

Animals: Twenty-one dogs.

Procedure: Total cystectomy was completed as follows: The whole bladder and urethra were removed, and the ureters were anastomosed to the skin in 1 case and to the vagina in 9 cases in females.

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Background: Sporadic cases and rare outbreaks of Zika Virus (ZIKV) have been reported in India since 2016. Between June to early September 2024; the city of Pune in western India was affected with a large outbreak of ZIKV. Here we report the analysis of epidemiological; clinical and genomic characteristics of the outbreak.

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The role of dual-energy computed tomography (DECT) in emergency radiology: a visual guide to advanced diagnostics.

Clin Radiol

February 2025

Radiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Via Francesco Sforza, 35, 20122, Milan, Italy.

Dual-energy computed tomography (DECT) has become an essential tool in emergency radiology, significantly enhancing diagnostic capabilities for a variety of acute conditions. By utilising two distinct X-ray energy spectra, DECT differentiates materials based on their attenuation properties, providing detailed insights into tissue composition and pathology. In emergency settings, DECT is used in thoracic imaging for the detection of pulmonary embolism, in abdominal imaging to enhance the diagnosis and characterisation of conditions such as pancreatitis, appendicitis, gastrointestinal bleeding, and bowel ischaemia and in the genitourinary system for identifying kidney stones, pyelonephritis, and urinary bleeding.

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Molecular analysis of acute pyelonephritis-excessive innate and attenuated adaptive immunity.

Life Sci Alliance

March 2025

Division of Microbiology, Immunology and Glycobiology, Department of Laboratory Medicine, Lund University, Lund, Sweden

This study investigated the molecular basis of disease severity in acute pyelonephritis (APN), a common and potentially life-threatening bacterial infection. Two cohorts of infants with febrile urinary tract infection were included. Renal involvement was defined by DMSA scans and molecular disease determinants by gene expression analysis and proteomic screens, at diagnosis and after 6 mo.

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Impact of urinary tract infection requiring hospital admission on short-term, mid-term and long-term renal outcomes in adult CKD patients - A potentially modifiable factor for CKD progression.

J Infect Public Health

February 2025

Division of Nephrology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:

Background: Urinary tract infection (UTI) or acute pyelonephritis can lead to renal scarring and impact the subsequent renal function progression. The aims of this study were to investigate the changes in renal function related to UTI requiring hospital admission (UTI/HA) and the association between UTI/HA and long-term renal outcomes in patients with chronic kidney disease (CKD).

Methods: This was a multicenter, retrospective observational study.

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