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The investigations were carried out on 20 sand rats (6 prediabetic, 6 diabetic and 8 normoglycemic animals). The cortices of adrenal glands were studied with histological methods. The thickness of the zona glomerulosa is in this 3 groups different. In the prediabetic group is the zona glomerulosa higher, in the diabetic group lower than the normoglycemic group. The relationship is 1.5 (normoglycemic group) : 2.9 (prediabetic group) : 0.8 (diabetic group). It is concluded that the zona glomerulosa in the prediabetic group is stimulated.

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