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Aim - to study functional organization of hemodynamic processes in brain basins of healthy children and children with mild mental retardation depending on the nature of asymmetry and gradient of cerebral blood filling are investigated. The research executed in the scientific laboratory of the special and inclusive education department of the Armenian State Pedagogical University after Kh. Abovyan and Armenian State Institute of Physical Culture and Sport.

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The features of functional organization of hemodynamic processes in brain basins of healthy children and children with mild mental retardation depending on the nature of asymmetry and gradient of cerebral blood filling are investigated. The study was executed in the scientific laboratory of the special and inclusive education department of the Armenian State Pedagogical University after Kh. Abovyan and Armenian State Institute of Physical Culture and Sport.

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Entropy Measures as Descriptors to Identify Apneas in Rheoencephalographic Signals.

Entropy (Basel)

June 2019

Biomedical Engineering Research Centre, Universitat Politècnica de Catalunya, CIBER of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 08028 Barcelona, Spain.

Rheoencephalography (REG) is a simple and inexpensive technique that intends to monitor cerebral blood flow (CBF), but its ability to reflect CBF changes has not been extensively proved. Based on the hypothesis that alterations in CBF during apnea should be reflected in REG signals under the form of increased complexity, several entropy metrics were assessed for REG analysis during apnea and resting periods in 16 healthy subjects: approximate entropy (ApEn), sample entropy (SampEn), fuzzy entropy (FuzzyEn), corrected conditional entropy (CCE) and Shannon entropy (SE). To compute these entropy metrics, a set of parameters must be defined a priori, such as, for example, the embedding dimension m, and the tolerance threshold r.

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Poincaré plot analysis of cerebral blood flow signals: Feature extraction and classification methods for apnea detection.

PLoS One

May 2019

Biomedical Engineering Research Centre, Universitat Politècnica de Catalunya, CIBER of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona, Spain.

Objective: Rheoencephalography is a simple and inexpensive technique for cerebral blood flow assessment, however, it is not used in clinical practice since its correlation to clinical conditions has not yet been extensively proved. The present study investigates the ability of Poincaré Plot descriptors from rheoencephalography signals to detect apneas in volunteers.

Methods: A group of 16 subjects participated in the study.

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Background: Impedance plethysmography applied to the head by using a pair of electrodes attached to the scalp surface is known as bipolar Rheoencephalography or REG I and was originally proposed to measure changes in cerebral blood volume related to the heartbeat. REG I was soon discarded in favor of other REG configurations, since most of the signal was shown to be heavily contaminated by the extracranial blood flow. The main goal of this study was to identify and compare the part of the REG I signal caused by scalp blood flow with that originating from non-extracranial sources.

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