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[Establishment of in-vitro mouse preantral follicle culture systems].
Wei Sheng Yan Jiu
March 2009
Department of Health Toxicology, Second Military Medical University, Shanghai 200433, China.
Objective: To develop mouse preantral follicle culture for toxicology study.
Methods: The ovaries were from prepubertal mice (C57B1/6JxCBA/Ca) (at the ages of 12-14 days). The ovaries were from prepubertal mice (C57B1/6JxCBA/Ca) (at the ages of 12-14 days).
A case of metastatic struma ovarii treated with 131I therapy: focus on preservation of fertility and selected review of the literature.
Gynecol Endocrinol
June 2008
Institute of Nuclear Medicine, Catholic University of Sacred Heart, Rome, Italy.
Struma ovarii is a rare monodermal ovarian teratoma composed predominantly of mature thyroid tissue. We describe herein the case of a 22-year-old woman who underwent a right salpingo-oophorectomy for struma ovarii at the age of 12 years, who was admitted 8 years later with signs and symptoms of a left pelvic tumor. Laparoscopy detected a left ovarian endometriotic cyst and multiple nodules on the pelvic peritoneum, right lateral abdominal wall, diaphragm, vesical plica and liver.
View Article and Find Full Text PDFAdrenal and ovarian hormonogenesis in a teenage girl with congenital lipoid adrenal hyperplasia (CLAH).
J Pediatr Endocrinol Metab
September 2004
Department of Pediatrics, Section of Endocrinology, The Children's Hospital/UCHSC, Denver, CO 80218, USA.
Effects of progesterone (P) and antiprogestin RU486 on LH and FSH release by incubated pituitaries from rats treated with the SERM LY11701 8-HCl and/or recombinant human FSH.
J Endocrinol Invest
September 2002
Department of Cell Biology, Physiology and Immunology, University of Córdoba, Spain.
The aim of the present study was to investigate the role of the estrogen (ES) background on the effects of P or its antagonist RU486 on basal and LHRH-stimulated LH and FSH secretion. To do this, pituitaries collected from: intact rats in proestrus; rats injected with the ES antagonist LY11701 8-HCl; rats injected with recombinant-human FSH (r-hFSH) to stimulate ovarian hormonogenesis; and rats injected with both LY11701 8-HCl and r-hFSH were incubated with or without LHRH (10 nM) in the presence of P (100 nM) or RU486 (10 nM). RU486 decreased basal and LHRH-stimulated release of LH and FSH and LHRH self-priming in pituitaries from control rats, while P increased both pituitary responsiveness and LHRH self-priming.
View Article and Find Full Text PDFRecombinant human thyrotropin for the diagnosis and treatment of a highly functional metastatic struma ovarii.
J Clin Endocrinol Metab
January 2000
Clinical Endocrinology Branch, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
The optimal treatment of metastatic thyroid cancer that produces high amounts of thyroid hormone has not been well defined. A 46-yr-old woman presented with a follicular thyroid carcinoma arising from a struma ovarii with hepatic metastases. After the removal of both the struma and the thyroid gland, the liver metastases showed evidence of a high degree of hormonogenesis.
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