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Effects of exercise on vascular remodelling and fetal growth in uncomplicated and abortion-prone mouse pregnancies.
Sci Rep
December 2024
Robinson Research Institute, School of Biomedicine, University of Adelaide, Adelaide, SA, Australia.
Studies in humans and rodents show exercise in pregnancy can modulate maternal blood pressure, vascular volume, and placental efficiency, but whether exercise affects early uteroplacental vascular adaptations is unknown. To investigate this, CBA/J female mice mated with BALB/c males to generate healthy uncomplicated pregnancies (BALB/c-mated) or mated with DBA/2J males to generate abortion-prone pregnancies (DBA/2J-mated), were subjected to treadmill exercise (5 days/week, 10 m/min, 30 min/day for 6 weeks before and throughout pregnancy), or remained sedentary. In uncomplicated pregnancies, exercise caused symmetric fetal growth restriction in fetuses evidenced by reductions in fetal weight, crown-to-rump length, abdominal girth and biparietal diameter.
View Article and Find Full Text PDFPL-TOSP, the Novel Entry Point in Transforaminal Endoscopic Spine Surgery: Radiological Analysis with Prospective Surgical Evaluation and Review of Literature of Various Skin Entry Points.
Asian J Neurosurg
December 2024
Department of Spine Surgery, Indore Spine Center, Indore, Madhya Pradesh, India.
Aim of this study was to analyze variation in angulation of trajectories of various skin entry points in transforaminal endoscopic spine surgery with change in the physical parameters, namely, weight, abdominal girth, and body mass index and to validate our hypothesis that posterolateral (PL)-tip of spinous process (TOSP) entry has minimal variation in the angle of trajectory as compared with currently available skin entry points. The study included an analysis of the functional outcomes of these patients who underwent transforaminal endoscopy using the novel PL-TOSP technique, assessing improvements in pain and disability. Entry point in transforaminal endoscopic lumbar discectomy (TELD) was taken as a rough distance of 10 to 12 cm from midline as proposed by Kambin whereas Yeung and Tsou advised entry point as distance between the center of the disc space and the posterior skin line measured on lateral.
View Article and Find Full Text PDFOutcomes and patient satisfaction after Penuma silicone implant surgery via two surgical approaches.
Ther Adv Urol
September 2024
Department of Urology, Rush University Medical Center, 1725 West Harrison Street, Suite #352, Chicago, IL 60612, USA.
Article Synopsis
- The Penuma implant is a silicone device designed to enhance the appearance of the flaccid penis in men who can achieve normal erections, with a focus on patient satisfaction and post-surgery complications after at least 6 months.
- A study analyzed outcomes from 92 cases, finding an average increase in flaccid length of 2.5 cm and girth of 3.1 cm, with a patient satisfaction rate of 82% and a majority willing to repeat the surgery.
- The research indicated that the lateral scrotal incision approach resulted in fewer complications and lower revision rates compared to the traditional infrapubic method, suggesting it might be the preferred surgical technique.
Seminal plasma uterine priming alters uterine transcriptomics and negatively impacts embryo growth and uterine artery resistance but not offspring liver transcriptomics in beef cattle.
J Anim Sci
January 2024
Department of Animal and Dairy Sciences, Mississippi State University, Mississippi State, MS 39762, USA.
Article Synopsis
- - The study investigates the effects of seminal plasma uterine priming at estrus on various reproductive and developmental outcomes in cattle, focusing on the uterus of the dam and her offspring.
- - Cows were treated with either seminal plasma or a control, and various measurements including uterine biopsies, embryo size, and calf growth were taken at distinct stages of gestation and post-birth.
- - Results showed changes in uterine gene expression, with notable differences in embryo size and calf heart girth, but no significant effects on birth weight or liver gene expression in the offspring at 30 days.
Hyaluronic acid and urology: a systematic review and meta-analysis.
Sex Med Rev
September 2024
Department of Urology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Article Synopsis
- The study reviews the use of hyaluronic acid as a nonsurgical treatment in urology, highlighting its potential and the current state of research.
- A comprehensive analysis was conducted on 33 studies, focusing on metrics such as penile girth and ejaculatory latency, with most studies showing positive outcomes and rare complications.
- Despite encouraging results, variability in study quality is noted, emphasizing the need for standardized approaches in future randomized controlled trials.
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