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Sleep Deprivation Elevates Resting and Exercise Blood Pressures and Augments Pressor Response at Exercise Onset.
Med Sci Sports Exerc
December 2024
College of Life and Health Sciences, Chubu University, Kasugai, Aichi, JAPAN.
Purpose: Sleep deprivation and elevated blood pressure (BP) increase the risk of cardiovascular diseases. However, the effects of sleep deprivation on BP response, especially at exercise onset remain unclear. We aimed to elucidate the effects of experimental sleep deprivation (ESD) on resting and exercise BPs, including that at exercise onset, and investigate whether a night-time nap during ESD changes the ESD-altered BP.
View Article and Find Full Text PDFDeconditioning in quiescent Crohn's Disease patients with heightened fatigue perception.
J Crohns Colitis
January 2025
Professor of Gastroenterology, Translational Medical Sciences, School of Medicine, Faculty of Medicine and Health Sciences, University of Nottingham; NIHR Nottingham Biomedical Research Centre, Nottingham.
Background & Objective: IBD fatigue aetiology is poorly understood. This study quantified body composition and physical function alongside proton magnetic resonance imaging (1H MRI) and spectroscopy (31P MRS) measures of organ structure and function in quiescent Crohn's Disease patients (CD) and healthy volunteers (HV), to identify a physiological basis for IBD fatigue.
Methods: Body composition was determined using DEXA and 1H MRI.
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Alzheimers Dement
December 2024
Aging Research Center, Karolinska Institutet, Stockholm, Sweden.
Background: Cardiorespiratory fitness (CRF), a proxy for cardiovascular and respiratory function, has been linked to health outcomes, but its association with cognition and dementia risk remains unclear. We aimed to investigate the association of CRF with domain-specific cognitive function and dementia risk, taking genetic predisposition for dementia into account.
Method: Within the UK Biobank, 61,214 dementia-free participants aged 39-70 (mean age: 56.
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Alzheimers Dement
December 2024
University of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA.
Background: Cardiorespiratory fitness (CRF) has been repeatedly linked to healthy brain and cognitive outcomes in aging. Treadmill-based graded maximal exercise testing (GXT) is a common technique for measuring CRF in exercise studies. Because it is often challenging for older adults to reach the commonly accepted criterion measure of oxygen consumption, alternate, submaximal measures have been explored.
View Article and Find Full Text PDFDementia Care Practice.
Alzheimers Dement
December 2024
Kentucky College of Osteopathic Medicine, PikeVille, KY, USA.
Background: Integrating humanoid robots, wearable sensors, and spatial technology into an intelligent dementia-friendly living space is crucial for tailoring personalized and supportive environments, thereby addressing the unique needs of individuals affected by dementia and maintaining quality of life.[1-10].
Methods: We programmed Pepper, a humanoid robot, for independent verbal communication to interact, tell jokes, and offer medications.
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