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Ophthalmol Glaucoma
February 2024
Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota. Electronic address:
Purpose: To investigate the in vivo effect of scleral buckle surgery on ocular biomechanics and aqueous humor dynamics.
Design: Prospective observational cross-sectional study.
Participants: Nine patients with unilateral 360 degree encircling scleral buckles without vitrectomy for rhegmatogenous retinal detachments, between 3 and 39 months postoperative.
J Glaucoma
March 2023
Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo.
Prcis: Decreasing aqueous outflow resistance at trabecular meshwork is the main mechanism of modified 360-degree suture trabeculotomy (ST), and the preoperative C-value, which shows aqueous outflow resistance, is likely to be useful for predicting intraocular pressure (IOP) reduction.
Purpose: To clarify the mechanism of IOP reduction and the preoperative prognostic predictor of modified 360-degree ST.
Materials And Methods: Forty-three eyes of 32 patients with glaucoma who underwent ST at Hokkaido University Hospital between April 2017 and February 2020 were enrolled.
Eye (Lond)
April 2022
Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Japan.
Purposes: To elucidate the mechanism of intraocular pressure (IOP) reduction by microhook ab interno trabeculotomy (μLOT), the aqueous humour outflow facility was compared preoperatively and post-operatively.
Methods: Fifty-one eyes (37 patients; mean age, 67.2 ± 11.
Eye (Lond)
September 2021
Department of Ophthalmology, St Thomas' Hospital, London, SE1 7EH, UK.
Purpose: High intensity focused ultrasound (HiFU) is a cyclodestructive therapy for controlling intraocular pressure (IOP) in glaucoma. The mechanism of action is thought to be through destruction of the ciliary epithelium as well as increased uveoscleral outflow. We reviewed the change in aqueous humour dynamics parameters including aqueous humour flow rate, tonographic outflow facility (TOF) and uveoscleral outflow at 12 months.
View Article and Find Full Text PDFOphthalmol Glaucoma
August 2021
St. Thomas' Hospital, London, United Kingdom; King's College London, London, United Kingdom. Electronic address:
Purpose: To investigate the effects of high-intensity focused ultrasound (HiFU) on aqueous humor dynamics in patients with glaucoma.
Design: Comparative, nonrandomized, interventional study.
Participants: Adult patients with a diagnosis of open-angle glaucoma or ocular hypertension with suboptimal intraocular pressure (IOP) control despite maximum medical treatment who required further IOP optimization.
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