Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/bja/45.7.704 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical Correlates of Efficacy of Pyridostigmine in the Treatment of Orthostatic Hypotension.
Hypertension
December 2024
Vanderbilt Autonomic Dysfunction Center, Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN. (L.E.O., A.D., C.A.S., A.G., B.K.B., S.P., I.B.).
Background: The cholinesterase inhibitor pyridostigmine is used to treat orthostatic hypotension by facilitating cholinergic neurotransmission in autonomic ganglia, thereby harnessing residual sympathetic tone to increase blood pressure (BP) preferentially in the upright posture. We hypothesized that less severe autonomic impairment was associated with greater pressor responses to pyridostigmine.
Methods: To identify predictors of pressor response, linear regression analyses between the effect of pyridostigmine on upright BP and markers of autonomic impairment were retrospectively conducted on 38 patients who had a medication trial with pyridostigmine (60 mg single dose).
Rational approach to fetal heart rate monitoring and management during the second stage of labor.
Eur J Obstet Gynecol Reprod Biol
December 2024
Direttore UOC Ostetricia e Ginecologia, Azienda Ospedaliera Universitaria di Parma, Professore Ordinario di Ginecologia e Ostetricia, Direttore della Scuola di Specializzazione in Ostetricia e Ginecologia, Presidente del CdS OstetriciaUniversità di Parma, Italy. Electronic address:
Second stage of labor is considered to be associated with an increased risk of intrapartum fetal hypoxic injury. This is due to a combination of several risk factors such as -the increased frequency, strength and duration of uterine contractions due to higher number and affinity of myometrial oxytocin receptors; -the Ferguson's reflex which leads to a reflex release of endogenous oxytocin in response of the distension of the cervix by descending fetal head in late stages of labor; maternal expulsive efforts with the Valsalva manoeuvre that may reduce maternal oxygenation, as well as reduce the venous return and maternal cardiac output due to increased intrathoracic pressure, winch may lead to reduced placental oxygenation; - and increased fetal intracranial pressure due to head compression leading to a potential decrease in fetal cerebral oxygenation. In addition, the umbilical cord often forms one or more loops around the fetal neck, which may get tightened as the head descends leading to an acute and intermittent cessation of fetal oxygenation.
View Article and Find Full Text PDFMaternal and fetal responses to acute high-intensity resistance exercise during pregnancy.
Br J Sports Med
December 2024
Program for Pregnancy and Postpartum Health, Physical Activity and Diabetes Laboratory, Faculty of Kinesiology, Sport, and Recreation, Women and Children's Health Research Institute, Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Objective: To examine maternal and fetal cardiovascular responses to high-intensity resistance exercise in pregnancy.
Methods: 10 healthy pregnant (26.4±3.
Patient Reported Outcomes Due to Bladder Neck Obstruction in Women Treated With Botulinum Toxin A Injection.
Neurourol Urodyn
November 2024
Department of Urology, Albany Medical Center, Albany, New York, USA.
Article Synopsis
- Primary bladder neck obstruction (BNO) is a condition where the bladder neck doesn't open properly during urination, causing symptoms without any anatomical blockage, potentially linked to nerve issues or anxiety.
- Botulinum toxin A (BoNT-A) is used as a treatment for women with BNO who haven't responded to traditional therapies, and this study reports on patient outcomes following BoNT-A treatment.
- Out of 18 women treated, 77% experienced improvement, particularly in symptoms like incomplete emptying and pelvic pain, based on self-reported assessments.
One artery to rule them all: A case of single coronary artery arising from the right sinus of Valsalva.
Radiol Case Rep
January 2025
General Hospital of Florina "Eleni Th. Dimitriou", Department of Cardiology, Egnatias 9, Florina 53100, Greece.
A single coronary artery (SCA) is a rare congenital anomaly with an incidence of 0.024 - 0.066% in angiographies and potential implications for adverse events depending on the course of the anomalous artery.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!