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The New-Meaning Objection: A Reply to Nicolò D'Agruma.
Cogn Sci
January 2025
Africa Institute for Research in Economics and Social Science, Mohammed VI Polytechnic University.
In our paper, "The reference of proper names" (2018), we raised and rebutted the "New-Meaning" objection to our methodology. Our rebuttal rested on theoretical considerations and experimental results. In "Do the Gödel vignettes involve a new descriptivist meaning?", Nicolò D'Agruma provides an interesting argument against our theoretical considerations (but does not address the experimental evidence).
View Article and Find Full Text PDFActive learning-assisted directed evolution.
Nat Commun
January 2025
Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.
Directed evolution (DE) is a powerful tool to optimize protein fitness for a specific application. However, DE can be inefficient when mutations exhibit non-additive, or epistatic, behavior. Here, we present Active Learning-assisted Directed Evolution (ALDE), an iterative machine learning-assisted DE workflow that leverages uncertainty quantification to explore the search space of proteins more efficiently than current DE methods.
View Article and Find Full Text PDFDistinctive Delta and Theta Responses in Deductive and Probabilistic Reasoning.
Brain Behav
January 2025
Research Institute for Health Sciences and Technologies (SABITA), Neuroscience Research Center, Clinical Electrophysiology, Neuroimaging and Neuromodulation Lab, Istanbul Medipol University, Istanbul, Turkey.
Introduction: The neural substrates of reasoning, a cognitive ability we use constantly in daily life, are still unclear. Reasoning can be divided into two types according to how the inference process works and the certainty of the conclusions. In deductive reasoning, certain conclusions are drawn from premises by applying the rules of logic.
View Article and Find Full Text PDFUnraveling the Relationship Between Vitamin D and Noncommunicable Diseases: A Systemic Review and Meta-Analysis.
Public Health Nurs
January 2025
Symbiosis College of Nursing, Symbiosis International (Deemed University), Pune, India.
Background: Subclinical vitamin D insufficiency is frequent in both developing and developed countries. Even after rickets was eliminated in the 1930s by fortifying milk, up to 1 billion people worldwide suffer from subclinical vitamin D deficiency (VDD). Numerous noncommunicable diseases (NCDs), including depression, autoimmune illnesses, diabetes, osteoporosis, and cardiovascular disease, are linked to this deficiency.
View Article and Find Full Text PDFThe Two-Spin Enigma: From the Helium Atom to Quantum Ontology.
Entropy (Basel)
November 2024
EPITA Research Laboratory, 14-16 Rue Voltaire, 94270 Le Kremlin-Bicêtre, France.
The purpose of this article is to provide a novel approach and justification of the idea that classical physics and quantum physics can neither function nor even be conceived without the other-in line with ideas attributed to, e.g., Niels Bohr or Lev Landau.
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