Bilirubin reacts with zinc acetate, cadmium acetate or cobaltous acetate in dry dipolar aprotic solvents to form highly coloured complexes. The complex formed in NN-dimethylformamide can be isolated as a solid with bilirubin:zinc:acetate:NN-dimethylformamide molar proportions of 1:3:2:2. Water will decompose these complexes, with the regeneration of bilirubin.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1177712PMC
http://dx.doi.org/10.1042/bj1330399DOI Listing

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