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CT scan-based morphometric comparison of human and canine lumbar spine generates instrumental data for intervertebral disc percutaneous surgery.
Osteoarthr Cartil Open
March 2025
Nantes Université, Oniris, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, UMR 1229, Nantes, F-44000, France.
Objective: This study aimed to describe the anatomical landmarks for intervertebral disc (IVD) percutaneous approaches (transpedicular TPA and transannular TAA) using CT scans in humans and dogs for regenerative medicine research.
Method: CT scans of 57 human (30 supine, 27 prone) and 49 canine (29 chondrodystrophic, 20 non-chondrodystrophic) lumbar spines were analyzed. Morphometric data, cutaneous landmarks, and approach angles were measured, with additional sections assessing nerve root distances from TPA routes.
Fundamentals of intervertebral disc degeneration and related discogenic pain.
World J Orthop
January 2025
Department of Orthopedics, The Third Medical Center, General Hospital of the Chinese People's Liberation Army, Beijing 100039, China.
Lumbar intervertebral disc degeneration is thought to be the main cause of low back pain, although the mechanisms by which it occurs and leads to pain remain unclear. In healthy adult discs, vessels and nerves are present only in the outer layer of the annulus fibrosus and in the bony endplate. Animal models, and histological and biomechanical studies have shown that annulus tear or endplate injury is the initiating factor for painful disc degeneration.
View Article and Find Full Text PDFQuantitative evaluation of lumbar intervertebral disc degeneration: a comparison of ultrashort time-to-echo T2* with T1rho relaxometry.
Acta Radiol
January 2025
Department of Radiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, PR China.
Background: Early detection of changes in lumbar intervertebral disc degeneration (IVDD) has great clinical significance. T1rho and UTE-T2* relaxometry are capable of providing information about biochemical changes in IVDD. However, they have not been previously analyzed and compared directly in the same patients.
View Article and Find Full Text PDF[Short-term effectiveness of uni-portal non-coaxial spinal endoscopic surgery via crossing midline approach in treatment of free lumbar disc herniation].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
January 2025
Department of Sports Medicine, First Affiliated Hospital of Kunming Medical University, Kunming Yunnan, 650032, P. R. China.
Objective: To investigate the short-term effectiveness of uni-portal non-coaxial spinal endoscopic surgery (UNSES) via crossing midline approach (CMA) in the treatment of free lumbar disc herniation (FLDH).
Methods: Between March 2024 and June 2024, 16 patients with FLDH were admitted and treated with UNSES via CMA. There were 9 males and 7 females with an average age of 55.
Multifidus fat infiltration negatively influences the postoperative outcomes in lumbar disc herniation following transforaminal approach percutaneous endoscopic lumbar discectomy.
Eur J Med Res
January 2025
Department of Orthopedic Surgery, Jiujiang University Clinical Medical College (Jiujiang University Affiliated Hospital), Jiujiang, 332006, China.
Purpose: This study aims to investigate the influence of multifidus muscle fat infiltration on clinical outcomes in lumbar disc herniation (LDH) undergoing percutaneous endoscopic lumbar discectomy (PELD).
Methods: A retrospective analysis was conducted on 224 patients who underwent lateral PELD, with complete one-year follow-up data. Patients were divided into two groups based on preoperative MRI evaluation of L4 multifidus muscle fat infiltration: a mild group (< 25%) and a severe group (≥ 25%).
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