Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Cortical dynamics in hand/forelimb S1 and M1 evoked by brief photostimulation of the mouse's hand.
bioRxiv
December 2024
Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Spiking activity along synaptic circuits linking primary somatosensory (S1) and motor (M1) areas is fundamental for sensorimotor integration in cortex. Circuits along the ascending somatosensory pathway through mouse hand/forelimb S1 and M1 were recently described in detail (Yamawaki et al., 2021).
View Article and Find Full Text PDFA brain-tumor neural circuit controls breast cancer progression in mice.
J Clin Invest
December 2023
Experimental Center of Basic Medicine, Chongqing Key Laboratory of Neurobiology, College of Basic Medical Sciences.
Article Synopsis
- Scientists studied how anxiety from tumors in mice affects their cancer growth!
- They found that certain brain cells (CRH neurons) get super active when there's a tumor, which makes the mice more anxious!
- Using special techniques, they showed that reducing this brain activity can help lower both anxiety and tumor growth, and they even found that an antianxiety medicine might help slow down cancer!
Synaptic alterations and neuronal firing in human epileptic neocortical excitatory networks.
Front Synaptic Neurosci
August 2023
Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Budapest, Hungary.
Epilepsy is a prevalent neurological condition, with underlying neuronal mechanisms involving hyperexcitability and hypersynchrony. Imbalance between excitatory and inhibitory circuits, as well as histological reorganization are relatively well-documented in animal models or even in the human hippocampus, but less is known about human neocortical epileptic activity. Our knowledge about changes in the excitatory signaling is especially scarce, compared to that about the inhibitory cell population.
View Article and Find Full Text PDFCell anatomy and network input explain differences within but not between leech touch cells at two different locations.
Front Cell Neurosci
July 2023
Department of Neuroscience, Computational Neuroscience, Faculty VI, University of Oldenburg, Oldenburg, Germany.
Mechanosensory cells in the leech share several common features with mechanoreceptors in the human glabrous skin. Previous studies showed that the six T (touch) cells in each body segment of the leech are highly variable in their responses to somatic current injection and change their excitability over time. Here, we investigate three potential reasons for this variability in excitability by comparing the responses of T cells at two soma locations (T2 and T3): (1) Differential effects of time-dependent changes in excitability, (2) divergent synaptic input from the network, and (3) different anatomical structures.
View Article and Find Full Text PDFUpper and lower motor neuron neurophysiology and motor control.
Handb Clin Neurol
August 2023
Faculdade de Medicina-Instituto de Medicina Molecular-Centro de Estudos Egas Moniz, Universidade de Lisboa, Lisbon, Portugal; Department of Neurology, Barts and London School of Medicine, Queen Mary University of London and Royal London Hospital, London, United Kingdom.
This chapter considers the principles that underlie neurophysiological studies of upper motor neuron or lower motor neuron lesions, based on an understanding of the normal structure and function of the motor system. Human motor neurophysiology consists of an evaluation of the active components of the motor system that are relevant to volitional movements. Relatively primitive motor skills include locomotion, much dependent on the spinal cord central pattern generator, reaching, involving proximal and distal muscles activation, and grasping.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!