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A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China.
Front Endocrinol (Lausanne)
January 2025
Department of Endocrinology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.
Context: There are limited real-world data evidence assessing the clinical characteristics of hospitalized osteoporotic fractures in China.
Objective: To investigate the clinical characteristics of hospitalized major osteoporotic fractures in Northeast China.
Methods: We identified hospitalized fracture patients aged 50 and over from the First Affiliated Hospital of Jinzhou Medical University between January 1, 2018, and December 31, 2022.
Potential antihyperlipidemic effects of myrcenol and curzerene in high-fat fed rats.
BMC Pharmacol Toxicol
January 2025
Evangelical College, N'Djamena, BP 1200, Chad.
The study evaluated the anti-hyperlipidemic effects of myrcenol and curzerene on a high fat diet induced hyperlipidemia rat model. Thirty male albino rats were fed on a high-fat diet for four months. The HFD-induced hyperperlipidemia rats were treated with rosuvastatin (10 mg/kg), curzerene (130 mg/kg) and myrcenol (100 mg/kg) for four weeks.
View Article and Find Full Text PDFDevelopment and external validation of the SMASHERS risk prediction model for aneurysmal subarachnoid haemorrhage in the general population: a population-based prospective cohort study.
BMJ Open
January 2025
Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, Netherlands
Objectives: Aneurysmal subarachnoid haemorrhage (ASAH) is a severe stroke type, preventable by screening for intracranial aneurysms followed by treatment in high-risk individuals. We aimed to develop and validate a risk prediction model for ASAH in the general population to identify high-risk individuals.
Design: We used the population-based prospective cohort studies of the United Kingdom (UK) Biobank for model development and the Trøndelag Health (HUNT) Study for model validation.
The long-term effects of cardiometabolic risk factors on mortality and life expectancy: evidence from a health check-up cohort study.
BMC Cardiovasc Disord
January 2025
Research Center for Humanities and Social Sciences, Academia Sinica, Taipei City, Taiwan.
Objective: Cardiometabolic risk factors significantly contribute to disease burden. This study explored the effects of hypertension (HTN), diabetes mellitus (DM), and hyperlipidemia (HLP) on mortality. It stratified findings by age group and comorbidity severity using the Charlson Comorbidity Index (CCI) score.
View Article and Find Full Text PDFLiver transplantation for homozygous familial hypercholesterolemia: a retrospective analysis from Chinese experience.
Orphanet J Rare Dis
January 2025
Department of Critical Liver Diseases, Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Background: Homozygous familial hypercholesterolaemia (HoFH) increases risk of premature cardiovascular events and cardiac death. In severe cases of HoFH, clinical signs and symptoms cannot be controlled well by non-surgical treatments, liver transplantation (LT) currently represents the viable option.
Method: To assess the clinical efficacy, prognosis, and optimal timing of LT for HoFH, a retrospective analysis was conducted on the preoperative, surgical conditions, and postoperative follow-up of children who received an LT for HoFH at the Beijing Friendship Hospital over the period from December 2014 to August 2022.
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