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Aging impairs deliberation and behavioral flexibility in inter-temporal choice.
Front Aging Neurosci
April 2015
Department of Neuroscience, University of Minnesota Minneapolis, MN, USA.
Inter-temporal choice depends on multiple, interacting systems, some of which may be compromised with age. Some of these systems may be responsible for ongoing trial-by-trial choice strategies. Some may represent the consequences of action.
View Article and Find Full Text PDFEffects of breastfeeding on body composition and maturational tempo in the rat.
BMC Med
April 2013
Division of Pediatric Endocrinology, Meyer Children's Hospital, Rambam Health Care Campus, Haaliya Street, Haifa 31096, Israel.
Background: Features of life history are subject to environmental regulation in the service of reproductive fitness goals. We have previously shown that the infant-to-childhood transition reflects the adaptive adjustment of an individual's size to the prevailing and anticipated environment.
Methods: To evaluate effects of weaning age on life-history traits in rats, we repeatedly measured length and body mass index (BMI), as well as physiological development and sexual maturation in pups weaned early (d16), normally (d21) or late (d26).
Theta-band phase locking of orbitofrontal neurons during reward expectancy.
J Neurosci
May 2010
Cognitive and Systems Neuroscience Group, Swammerdam Institute for Life Sciences-Center for Neuroscience, University of Amsterdam, 1090 GE Amsterdam, The Netherlands.
The expectancy of a rewarding outcome following actions and cues is coded by a network of brain structures including the orbitofrontal cortex. Thus far, predicted reward was considered to be coded by time-averaged spike rates of neurons. However, besides firing rate, the precise timing of action potentials in relation to ongoing oscillations in local field potentials is thought to be of importance for effective communication between brain areas.
View Article and Find Full Text PDFNeuronal activity in rat medial prefrontal cortex during sucrose solution intake.
Neuroreport
September 2009
Institute of Physiology and Neurophysiology Research Group of the Hungarian Academy of Sciences, Pécs University Medical School, Pécs H-7643, Hungary.
The rat's prefrontal cortex plays a role in integration of feeding-related information. In this study, we investigated the neuronal activity changes of medial prefrontal cortex during licking of sucrose solution by freely moving rats. We found two different types of excitatory and two different types of inhibitory single neuron responses time locked to the beginning of the licking clusters.
View Article and Find Full Text PDFA comparison of responses and stimuli as time markers.
Behav Processes
June 2009
Department of Psychology, Brown University, Providence, RI 02912, USA.
A rat's behavior, as well as a stimulus, may be a time marker. But do they lead to similar performance? Eight rats were trained on a 20-s DRL procedure in which head-entry responses were time markers, i.e.
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