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[Establishment and evaluation of a modified plasma protamine paracoagulation test].
Nan Fang Yi Ke Da Xue Xue Bao
September 2011
173 Clinic, 421 Hospital of PLA, Huizhou 516008, China.
Objective: To establish a modified plasma protamine paracoagulation test.
Methods: Plasma protamine paracoagulation, modified plasma protamine paracoagulation and D-dimer (D-D) tests were performed for the plasma samples collected from 98 cases of disseminated intravascular coagulation (DIC) and 156 normal subjects. The sensitivity and specificity of the 3 tests were analyzed.
Sulfite-alkaline method after Rampling and Gaffney is proposed for measuring fibrinogen and fibrin degradation products in cadaveric blood. Normal values for cadaveric blood are determined and qualitative paracoagulation tests proposed. Such biochemical studies can be used, along with histological, for more accurate postmortem diagnosis of the DIC syndrome.
View Article and Find Full Text PDFParameters were studied characterising the system of blood aggregate state control (BASC) in 693 patients with chronic gastritis and duodenitis. Suggested in the paper are six variants of the hemocoagulation and fibrinolysis inadequacy, such as latent hypercoagulation (a decline in spontaneous fibrinolysis), manifest hypercoagulation (enhanced tolerability of plasma to heparin), isolated paracoagulation (positive fibrinogen B or ethanol test), latent hypocoagulation (clot retraction is reduced or levels of fibrinogen are raised), structural hypocoagulation (spontaneous fibrinolysis is on the increase), manifest hypocoagulation (lowered tolerance of plasma to heparin). An algorithm of the BASC system is submitted allowing the diagnosis to be rendered automatic and differentiated therapy treatments to be prescribed.
View Article and Find Full Text PDF[Effect of oxygen aeroions on hemostasis and development of arteriosclerosis in hypodynamia].
Patol Fiziol Eksp Ter
November 1996
Experiments on 50 rabbits examined the hemostatic effects of negative oxygen aeroions (AI). In control experiments, keeping the animals under hypodynamia led to 40% animal death, significant aortic atherosclerosis and myocardial infarction. The animals developed the thrombohemorrhagic syndrome with hypercoagulemia and drastically suppressed blood fibrinolytic activity.
View Article and Find Full Text PDF[Disseminated intravascular coagulations].
Cah Anesthesiol
January 1997
Service de Réanimation, Hôpital Saint-Antoine, Paris.
Disseminated intravascular coagulation (DIC) syndromes can be defined as the formation of fibrin deposits within the microcirculation, occurring in definite clinical situations. Their biological counterpart is a consumption coagulopathy. The clinical profiles of DIC have been well known for decades, are multiform and range from latency to overwhelming haemorrhagic diatheses, including also characteristic but rare situations, such as purpura fulminans, acral cyanosis and pictures resembling thrombotic thrombocytopenic purpura or haemolytic-uraemic syndrome.
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