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Confirmatory diagnosis and successive chemotherapeutic treatments of metastatic skeletal sarcoma: A case report.
Oncol Lett
March 2025
Department of Medical Oncology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo 135-8550, Japan.
sarcoma is rare and its clinical features remain unclear. Given the similarity in presentation, it is possible that previously reported cases of Ewing-like adamantinoma may have been sarcoma. The present case report describes a tumor in a 55-year-old man that was originally thought to be a Ewing-like adamantinoma, but was recently found to be an sarcoma following direct sequencing.
View Article and Find Full Text PDFA more significant role for insertion sequences in large-scale rearrangements in bacterial genomes.
mBio
January 2025
Microbial Evolutionary Dynamics Group, Department of Theoretical Biology, Max Planck Institute for Evolutionary Biology, Plön, Germany.
Article Synopsis
- * Sometimes TSDs are absent due to degeneration, recombination between ISs, or adjacent deletions, which are common occurrences illustrated by data from the Lenski long-term evolution experiment.
- * The study proposes that certain IS movements associated with large-scale genomic rearrangements may not generate TSDs and provides observations of such events, suggesting that IS activity could drive significant genomic changes like deletions and duplications.
First Report of Causing Bacterial Blight on in China.
Plant Dis
November 2024
Qujing Normal University, Qujing Normal University Sanjiang Avenue, Qujing, China, 650011;
Article Synopsis
- Amorphophallus konjac, or konjac, is a valuable plant in Asia, known for both economic and medicinal properties, but it is facing a leaf blight outbreak in Yunnan, China as of July 2024.
- The disease causes brown lesions on leaves that worsen over time, leading to significant drops in plant health and corm yield.
- To identify the bacteria responsible, researchers isolated samples, characterized them using genetic sequencing, and found that their isolates closely resembled a strain of K. cowanii.
A finite element model for biomechanical characterization of ex vivo peripheral nerve dysfunction during stretch.
Physiol Rep
November 2024
Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Peripheral nerve damage can cause debilitating symptoms ranging from numbness and pain to sensory loss and atrophy. To uncover the underlying mechanisms of peripheral nerve injury, our research aims to develop a relationship between biomechanical peripheral nerve damage and function through finite element modeling. A noncontact, ex vivo electrophysiology chamber, capable of axially stretching explanted nerves while recording electrical signals, was used to investigate peripheral nerve injury.
View Article and Find Full Text PDFCase report: Extraskeletal mesenchymal chondrosarcoma with a rare metastasis to the pancreas.
Front Oncol
October 2024
Department of Radiology, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.
Background: Extraskeletal mesenchymal chondrosarcoma (ESMC), an uncommon and highly aggressive form of chondrosarcoma, is characterized by its mesenchymal origin and absence of skeletal involvement. Only a few cases of primary ESMC with metastasis to the pancreas have been reported so far. In this study, we present a case of ESMC in the left thigh with a solitary pancreatic metastasis in a 45-year-old woman.
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