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Assessing fluid responsiveness by using functional hemodynamic tests in critically ill patients: a narrative review and a profile-based clinical guide.
J Clin Monit Comput
January 2025
IRCCS Humanitas Research Hospital, via Manzoni 56, Rozzano - Milan, 20089, Italy.
Fluids are given with the purpose of increasing cardiac output (CO), but approximately only 50% of critically ill patients are fluid responders. Since the effect of a fluid bolus is time-sensitive, it diminuish within few hours, following the initial fluid resuscitation. Several functional hemodynamic tests (FHTs), consisting of maneuvers affecting heart-lung interactions, have been conceived to discriminate fluid responders from non-responders.
View Article and Find Full Text PDFAcute selective serotonin-reuptake inhibition elevates basal ventilation, attenuates the rebreathing ventilatory response, independent of cerebral perfusion.
J Appl Physiol (1985)
January 2025
Centre for Heart, Lung and Vascular Health, University of British Columbia - Okanagan Campus, Kelowna, BC, Canada.
Serotonin (5-HT) is integral to signalling in areas of the brainstem controlling ventilation and is involved in central chemoreception. Selective serotonin reuptake inhibitors (SSRIs), used to effectively increase 5-HT concentrations, are commonly prescribed for depression. The effects of SSRIs on the control of breathing and the potential influence of cerebral blood flow (CBF) have not been directly assessed.
View Article and Find Full Text PDFEssential oil of Lippia origanoides as an anesthetic for Piaractus mesopotamicus: implications for induction and recovery times, ventilatory frequency and blood responses after biometric management.
Braz J Biol
January 2025
Universidade Federal de Mato Grosso do Sul - UFMS, Programa de Pós-graduação em Ciência Animal, Campo Grande, MS, Brasil.
This study evaluated the use of the essential oil of Lippia origanoides (EOLO) as an anesthetic for juvenile pacu, Piaractus mesopotamicus. Two experiments were performed. In Experiment I, anesthetic induction and recovery times and ventilatory frequency (VF) were determined for fish (n= 48; 29.
View Article and Find Full Text PDFCigarette Smoking Impairs Cardiorespiratory and Metabolic Response at Peak Incremental Exercise and during Recovery in Young, Physically Active Adults.
Med Sci Sports Exerc
November 2024
Department of Biomedical Sciences for Health, Università degli Studi di Milano, ITALY.
Purpose: Cigarette smoking (CS) induces systemic changes that impair cardiorespiratory and muscular function both at rest and during exercise. Although these abnormalities are reported in sedentary, middle-aged smokers (SM) with pulmonary disease, few and controversial studies focused on young, physically active SM at the early stage of smoking history. This study aimed at assessing the impact CS on cardiorespiratory and metabolic response during an incremental test and the subsequent recovery in young, physically active SM without known lung or cardiovascular disease.
View Article and Find Full Text PDFUnraveling the Role of Oxygen Pulse Variability in Endurance Exercise Training in Individuals with COPD: A Novel Approach to Response of Oxygen Pulse and Quality of Life in Pulmonary Rehabilitation.
Int J Chron Obstruct Pulmon Dis
January 2025
Division of Pulmonary Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan, Republic of China.
Background: Chronic obstructive pulmonary disease (COPD) is characterized by airway inflammation, airflow limitation, reduced health-related quality of life (HRQL), and exercise intolerance. Pulmonary rehabilitation (PR) is essential for COPD management, but outcomes may be influenced by individual physiological factors. Cardiopulmonary exercise testing (CPET) measures oxygen pulse (O2P), an indicator of stroke volume, yet the impact of baseline O2P on PR effectiveness remains unclear.
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