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Application value of continuous nursing in the treatment of obese patients with laparoscopic sleeve gastrectomy.

Am J Transl Res

December 2024

Department of Pancreatic and Metabolic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University Nanjing 210008, Jiangsu, China.

Aim: To explore the value and effectiveness of continuous nursing in obese patients undergoing laparoscopic sleeve gastrectomy.

Methods: A total of 164 obese patients who were admitted to Nanjing Drum Tower Hospital and underwent planned laparoscopic sleeve gastrectomy in 2022 were retrospectively selected as the control group, and another 164 obese patients undergoing the same surgery in 2022 were chosen as the research group. The control group received routine care, while the research group received continuous nursing care.

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Objectives The study aimed at estimating the triglyceride glucose (TyG) index in patients with ischemic stroke, exploring the correlation between the TyG index and the prognosis of ischemic stroke, and studying the clinical outcome in patients with acute ischemic stroke (AIS) in association with the TyG index. Methods An observational study was conducted on 105 patients with a history of AIS presenting within 24 hours. The TyG index was estimated, and the clinical outcome was studied.

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Comparison of Influence of Office and 24-h Central Aortic Blood Pressure on Target Organ Damage in Hypertension.

J Clin Hypertens (Greenwich)

January 2025

Department of Geriatrics, Medical Center on Aging of Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

The aim of this study was to explore whether 24-h ambulatory central (aortic) blood pressure (BP) has an advantage over office central aortic BP in screening for hypertension-mediated target organ damage (HMOD). A total of 714 inpatients with primary hypertension and the presence of several cardiovascular risk factors or complications involving clinical HMOD were enrolled. Twenty-four hour central aortic BP was measured by means of a noninvasive automated oscillometric device (Mobil-O-Graph).

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The discrepancy between donor organ availability and demand leads to a significant waiting-list dropout rate and mortality. Although quantitative tools such as the Donor Risk Index (DRI) help assess organ suitability, many potentially viable organs are still discarded due to the lack of universally accepted markers to predict post-transplant outcomes. Normothermic machine perfusion (NMP) offers a platform to assess viability before transplantation.

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Aims: To assess the utility of reanalysing GCK variants of uncertain significance (VUS) as an intervention to improve the detection of monogenic diabetes.

Methods: We examined GCK VUS in a local cohort of individuals with suspected monogenic diabetes and re-curated each variant against the recent ClinGen GCK-specific variant classification guidelines.

Results: Variant reanalysis achieved a new 'likely pathogenic' classification (i.

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