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Background: Leptospirosis is an acute zoonotic disease caused by pathogenic , primarily transmitted to humans through contact with water or soil contaminated by the bacteria. It is globally distributed, with heightened prevalence in tropical regions. While prior studies have examined the pathophysiology, epidemiology, and risk factors of leptospirosis, few have explored trends and emerging topics in the field.

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sp. nov, . sp. nov, . sp. nov, . sp. nov and . sp. nov: five new species isolated from water sources in the Midwestern United States.

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Infectious Bacterial Diseases Research Unit, Agricultural Research Service, U.S. Department of Agriculture, Ames, IA, USA.

Isolates of spp. were cultured from water sources at five different sites in central Iowa in the Midwestern United States and characterized by whole-genome sequencing. Isolates were helix-shaped and motile.

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spp. infection in small ruminants is usually asymptomatic or presents nonspecific clinical signs and has an economic impact on goat farming and public health. The aim of this study was to carry out a systematic review with meta-analysis on the global seroprevalence and distribution of leptospirosis in goats.

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Article Synopsis
  • The study investigates the role of Toll-like receptor 2 (TLR2) in leptospirosis, a disease not well understood in relation to TLR2 involvement.
  • A systematic review was conducted on various studies with 35 articles selected, analyzing TLR2's expression and its association with immune responses during leptospirosis.
  • Results showed that while TLR2 was more consistently expressed in experiments, human data yielded mixed findings, indicating a need for more research on TLR2's role in human leptospirosis and its interaction with other receptors like TLR4 and TLR5.
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Grenadian cats as potential reservoir for Leptospira.

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St. George's University, School of Veterinary Medicine, Department of Pathobiology, Grenada, West Indies.

Leptospirosis is a spirochetal disease caused by Leptospira spp. bacteria with global distribution affecting multiple mammalian species, including humans. The disease is endemic in many geographic areas and is of particular concern in tropical regions with abundant rainfall, such as the Caribbean.

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