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Comparison of hypothermic and normothermic targeted temperature management in out-of-hospital cardiac arrest patients with acute coronary syndrome: a nationwide retrospective study.
Crit Care
January 2025
Division of Environmental Medicine and Population Services, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.
Background: Targeted temperature management (TTM) is considered a beneficial treatment for improving outcomes in patients with OHCA due to acute coronary syndrome (ACS). The comparative benefits of hypothermic TTM (32-34°C) versus normothermic TTM (35-36°C) are unclear. This study compares these TTM strategies in improving neurological outcomes and survival rates in OHCA patients with ACS.
View Article and Find Full Text PDFRisk factors for intraoperative hypothermia in patients receiving lung transplants.
J Thorac Dis
November 2024
Operating Room, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Background: Intraoperative hypothermia (IOH) has a high incidence in lung transplantation, which is considered to be an important factor affecting perioperative morbidity and mortality. Therefore, it is crucial to prevent IOH during lung transplantation. This study aimed to identify risk factors for IOH in patients receiving lung transplants, and to develop a risk model for predicting IOH.
View Article and Find Full Text PDFTreating deep sternal wound infection with pectoralis major flap transposition: a systemic factor analysis of efficacy and safety.
J Thorac Dis
November 2024
Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Article Synopsis
- - Deep sternal wound infection (DSWI) is a serious complication after cardiac surgery, and while various treatments exist, many have limitations; thus, the study explores pectoralis major flap transposition (PMFT) as a potential effective method.
- - A study of 785 DSWI patients treated with PMFT found that 90.3% healed successfully, while 9.7% experienced delayed healing or death; additional risk factors for poorer outcomes included diabetes, obesity, and a history of smoking.
- - The results suggest that PMFT is a safe treatment option for DSWI, but patients with specific risk factors should be monitored closely, and further research is recommended to better understand these relationships.
Outcomes in Neonates Receiving Therapeutic Hypothermia and Extracorporeal Membrane Oxygenation versus Extracorporeal Membrane Oxygenation Alone.
Am J Perinatol
December 2024
Division of Neonatology, Department of Pediatrics, Hassenfeld Children's Hospital at NYU Langone, New York University Grossman School of Medicine, New York, New York.
Objective: This study aimed to examine survival and outcomes in neonates who received therapeutic hypothermia (TH) for neonatal encephalopathy (NE) and extracorporeal membrane oxygenation (ECMO) versus ECMO alone.
Study Design: This is a retrospective review of Extracorporeal Life Support Organization (ELSO) Registry data from 2007 to 2017 for neonates undergoing ECMO and TH for NE (TH/ECMO) or ECMO alone. Primary outcomes were ECMO survival and survival to discharge.
Associations of long-term hyperoxemia, survival, and neurological outcomes in extracorporeal cardiopulmonary resuscitation patients undergoing targeted temperature management: A retrospective observational analysis of the SAVE-J Ⅱ study.
Resusc Plus
December 2024
Department of Emergency, Disaster and Critical Care Medicine, Kagawa University Hospital, Kagawa, Japan.
Article Synopsis
- - ECPR can enhance survival and neurological recovery for patients suffering from out-of-hospital cardiac arrest (OHCA), but elevated levels of arterial oxygen can hinder these outcomes, particularly in the context of targeted temperature management (TTM).
- - This study analyzed data from a larger registry of ECPR cases, focusing on the impact of prolonged hyperoxemia, defined as a partial pressure of arterial oxygen (PaO) of 300 mmHg or higher, during the initial days of intensive care.
- - Findings indicate that prolonged hyperoxemia negatively affects both survival and neurological recovery post-ECPR, with factors such as age and initial heart rhythm also playing critical roles in patient outcomes.
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