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PLoS Negl Trop Dis
December 2023
Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, PR China.
Background: Cathepsin L, a lysosomal enzyme, participates in diverse physiological processes. Recombinant Trichinella spiralis cathepsin L domains (rTsCatL2) exhibited natural cysteine protease activity and hydrolyzed host immunoglobulin and extracellular matrix proteins in vitro, but its functions in larval invasion are unknown. The aim of this study was to explore its functions in T.
View Article and Find Full Text PDFParasitol Int
October 2023
Medical Parasitology Department, Faulty of Medicine, Tanta University, Egypt; Medical Parasitology Subunit, Pathology Department, College of Medicine, Jouf University, Sakaka, Saudi Arabia.
Trichinella spiralis (T. spiralis)-induced myopathy is an inflammatory myopathy that is difficult to treat unless the parasite is combated in its early intestinal phase before it reaches the muscles. This study aimed to evaluate the effect of local mesenchymal stem cell (MSC) therapy on T.
View Article and Find Full Text PDFActa Trop
May 2023
Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou 450052, China. Electronic address:
Trichinellosis is a major zoonotic parasitosis which is a vital risk to meat food safety. It is requisite to exploit new strategy to interdict food animal Trichinella infection and to obliterate Trichinella from food animals to ensure meat safety. Mannose is an oligosaccharide that specifically binds to the carbohydrate-recognition domain of C-type lectin; it has many physiological functions including reliving inflammation and regulating immune reaction.
View Article and Find Full Text PDFVet World
September 2022
Department of Microbiology and Biotechnology, Faculty of Veterinary and Livestock Technology, Saken Seifullin Kazakh Agrotechnical University, 62 Zhenis Avenue, Nur-Sultan 010000, Kazakhstan.
Background And Aim: Trichinellosis remains a dangerous disease for humans and animals, which can lead to a lethal outcome. The study of specific body reactions in response to invasion by different types of can help in the early diagnosis of the disease. This study aimed to investigate the hematological, biochemical, and serological characteristics of rabbits experimentally infected with trichinellosis, as well as the possibility of using changes in these parameters at various disease stages for early hematological, biochemical, and serological diagnosis of trichinellosis.
View Article and Find Full Text PDFParasitol Int
October 2021
Laboratory of Parasitology, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Sagamihara, Kanagawa 252-5201, Japan; Yamazaki University of Animal Health Technology, 4-7-2 Minami-osawa, Hachioji, Tokyo 192-0364, Japan. Electronic address:
Experimental infection with Trichinella pseudospiralis larvae in red-eared slider Trachemys scripta was carried out. Ten turtles were divided into 3 groups and kept at different temperature (38, 32 and 28 °C). The turtles were fed mice muscles which were infected with T.
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