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Multi-effect coupling enhanced PtPdRhFeCu HEA/N-Cu-ZnSe@C biosensing device for pesticide residue detection in fruits and vegetables with ultra-low detection limit.
Food Chem
March 2025
Hebei Key Laboratory of Applied Chemistry, Key Laboratory of Heavy Metal Deep-Remediation in Water and Resource Reuse, College of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, China; Tianjin Key Laboratory of Multiplexed Identification for Port Hazardous Chemicals,State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China. Electronic address:
Article Synopsis
- Monitoring pesticide residues in food is crucial for health and quality, necessitating advanced detection techniques.
- An ultrasensitive electrochemical biosensor has been developed using innovative materials that enhance electronic properties and improve pesticide analysis performance.
- This biosensor achieves extremely low detection limits and wide detection ranges for specific pesticides, promoting its application in food safety and environmental monitoring.
Effects of chronic insecticide exposure on neuronal network development in vitro in rat cortical cultures.
Arch Toxicol
November 2024
Neurotoxicology Research Group, Division of Toxicology, Faculty of Veterinary Medicine, Institute for Risk Assessment Sciences (IRAS), Utrecht University, P.O. Box 80.177, NL-3508 TD, Utrecht, The Netherlands.
Developmental exposure to carbamates, organophosphates, and pyrethroids has been associated with impaired neurodevelopmental outcomes. Sex-specific differences following chronic insecticide exposure are rather common in vivo. Therefore, we assessed the chronic effects of in vitro exposure to different carbamates (carbaryl, methomyl and aldicarb), organophosphates [chlorpyrifos (CPF), chlorpyrifos-oxon (CPO), and 3,5,6,trichloropyridinol (TCP)], and pyrethroids [permethrin, alpha-cypermethrin and 3-phenoxy benzoic acid (3-PBA)] on neuronal network development in sex-separated rat primary cortical cultures using micro-electrode array (MEA) recordings.
View Article and Find Full Text PDFThe novel hydrolase IpcH initiates the degradation of isoprocarb in a newly isolated strain Rhodococcus sp. D-6.
J Hazard Mater
September 2024
Department of Microbiology, College of Life Sciences, Nanjing Agricultural University, Key Laboratory of Agricultural and Environmental Microbiology, Ministry of Agriculture and Rural Affairs, Nanjing 210095, China. Electronic address:
Article Synopsis
- Isoprocarb (IPC) is a type of insecticide that can harm the environment and non-target organisms, but its breakdown process hasn't been studied until now.
- Researchers isolated a new strain called D-6 from the Rhodococcus genus, which can degrade IPC, and identified a unique enzyme, IpcH, responsible for breaking down IPC into a less harmful compound, 2-isopropylphenol (IPP).
- The study highlights IpcH's effectiveness against various carbamate insecticides and suggests that strain D-6 could be useful for cleaning up IPC-contaminated environments by reducing its toxicity.
Effects of acute insecticide exposure on neuronal activity in vitro in rat cortical cultures.
Neurotoxicology
May 2024
Neurotoxicology Research Group, Division of Toxicology, Institute for Risk Assessment Sciences (IRAS), Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.177, TD, Utrecht NL-3508, the Netherlands.. Electronic address:
Article Synopsis
- Pesticides, including carbamates, organophosphates, organochlorines, and pyrethroids, are linked to health issues like neurotoxicity, with some studies indicating these effects can vary by sex.
- In experiments using female and male rat cortical cultures, specific pesticides were found to impact neuronal network function differently, suggesting carbaryl and organophosphates like CPF and CPO reduce neuronal activity, with CPO being the most impactful.
- The study highlights that certain pesticides can lead to increased or decreased neuronal activity, and that females may be more sensitive to specific compounds like endosulfan, demonstrating the importance of considering sex in neurotoxicity research.
Aldicarb disturbed bile acid, steroid hormone and oxylipin homeostasis in C57BL/6 J mice.
Ecotoxicol Environ Saf
April 2024
School of Marine Sciences, Nanjing University of Information Science and Technology, Nanjing 210044, China; Key Laboratory of Hydrometeorological Disaster Mechanism and Warning of Ministry of Water Resources, Nanjing University of Information Science and Technology, Nanjing 210044, China. Electronic address:
Mounting evidence has shown that the gut microbiota plays a key role in human health. The homeostasis of the gut microbiota could be affected by many factors, including environmental chemicals. Aldicarb is a carbamate insecticide used to control a variety of insects and nematode pests in agriculture.
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