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Osmotolerance reflected in mitochondrial respiration of Mytilus populations from three different habitat salinities.
Mar Environ Res
January 2025
Marine Biology, Institute for Biological Sciences, University of Rostock, Albert-Einstein-Strasse 3, D - 18059, Rostock, Germany; Department of Maritime Systems, Interdisciplinary Faculty, University of Rostock, Albert-Einstein-Strasse 21, D-18059, Rostock, Germany.
Mussels from the Mytilus edulis species complex experience a salinity gradient from the North Sea into the Baltic Proper ranging from 32 to 5. As osmoconformers, they adjust their internal osmolarity to match that of their surroundings, which presents a significant challenge to the metabolic machinery, including their mitochondria. We hypothesized that the osmotic optima for the mitochondrial function of mussels matches the prevailing habitat salinity and is accompanied by a population specific metabolite profile.
View Article and Find Full Text PDFA new approach to off-gas analysis for shaken bioreactors showing high CTR and RQ accuracy.
J Biol Eng
January 2025
AVT - Biochemical Engineering, RWTH Aachen University, Forckenbeckstr. 51, D-52074, Aachen, Germany.
Background: Shake flasks are essential tools in biotechnological development due to their cost efficiency and ease of use. However, a significant challenge is the miniaturization of process analytical tools to maximize information output from each cultivation. This study aimed to develop a respiration activity online measurement system via off-gas analysis, named "Transfer rate Online Measurement" (TOM), for determining the oxygen transfer rate (OTR), carbon dioxide transfer rate (CTR), and the respiration quotient (RQ) in surface-aerated bioreactors, primarily targeting shake flasks.
View Article and Find Full Text PDFSex-based variations in breath-holding: oxygen storage and diving response among non-divers.
Front Physiol
January 2025
Department of Health Sciences, Environmental Physiology Group, Mid Sweden University, Östersund, Sweden.
Breath-hold diving performances are typically better in men than in women. However, it is still being determined if there are differences in the physiological responses to breath-holding between the sexes. We conducted a study comparing the maximum breath-hold duration, heart rate (HR) reduction, peripheral oxygen saturation (SpO), and spleen volume and contraction in 37 men and 44 women, all of whom had no prior breath-holding experience.
View Article and Find Full Text PDFEffect of Aerobic Exercises on Lung Function in Women With Fibromyalgia: A Randomized Controlled Trial.
J Phys Act Health
January 2025
Department of Physiotherapy, Faculty of Allied Medical Sciences, Middle East University, Amman, Jordan.
Background: Aerobic exercises (AEs) have gained much interest in managing fibromyalgia (FM). This trial aimed to find out how AEs affect women with FM in terms of lung function, chest expansion, dyspnea, exercise capacity, and quality of life.
Methods: Eighty FM-diagnosed women were allocated randomly into 2 equal-sized groups.
Inhibition of hippocampal interleukin-6 receptor-evoked signalling normalises long-term potentiation in dystrophin-deficient mice.
Brain Behav Immun Health
February 2025
Department of Physiology, School of Medicine, University College Cork, Western Road, Cork, Ireland.
Duchenne muscular dystrophy (DMD), an X-linked neuromuscular disorder, characterised by progressive immobility, chronic inflammation and premature death, is caused by the loss of the mechano-transducing signalling molecule, dystrophin. In non-contracting cells, such as neurons, dystrophin is likely to have a functional role in synaptic plasticity, anchoring post-synaptic receptors. Dystrophin-expressing hippocampal neurons are key to cognitive functions such as emotions, learning and the consolidation of memories.
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