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Establishment and verification of reference intervals for blood cell analysis in extremely high altitude.
Front Physiol
October 2024
Extracorporeal Circulation Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Objective: This study aimed to establish the reference intervals for complete blood count (CBC) in healthy adults at very high altitudes.
Methods: This study recruited 4,863 healthy adults (3,598 males and 1,265 females) who received routine health check-ups at Ali District People's Hospital from January 2019 to December 2021 through the LIS system. CBC was detected by the XT-4000i automatic cell analyzer and statistically analyzed by SPSS 23.
Cryoglobulinemia Associated With Multiple Myeloma in a Dog Presenting With Epistaxis and Skin Lesions.
Vet Med Sci
November 2024
Easter Bush Pathology, The Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Edinburgh, UK.
A 10-year-old female neutered Labrador Retriever presented with epistaxis, discoloration and crusting of the nose and a necrotic lesion on the lip. Bloodwork revealed pancytopenia, azotemia, hypoalbuminemia and hyperglobulinemia. Aggregates of amorphous basophilic material were seen in a room-temperature blood smear which were not present in the sample after warming to 37°C, and grossly a cryoprecipitate was noted in the patient's serum at 4°C.
View Article and Find Full Text PDFSynthesis and Antiallergic Activity of Dicoumarin Derivatives.
Molecules
August 2024
The Key Laboratory of Chinese Medicine Research and Development in Hebei Province, Traditional Chinese Medicine Institute, Chengde Medical University, Chengde 067000, China.
Allergies are one of the diseases whose incidence rates have increased in recent years due to the greenhouse effect and extreme climate change. Therefore, the development of new antiallergic drugs has attracted the interest of researchers in chemistry and pharmacy fields. Dicoumarin is a coumarin derivative with various biological activities, but its antiallergic activity has not been evaluated.
View Article and Find Full Text PDFPathogenicity of Duck Adenovirus Type 3 in Chickens.
Animals (Basel)
August 2024
Key Laboratory of Veterinary Pathobiology and Disease Control, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Article Synopsis
- Duck adenovirus Type 3 (DAdV-3) was found to be pathogenic in chickens, leading to a 100% mortality rate in chicks inoculated subcutaneously, and a 26.7% death rate in those infected via eye-nose drop.
- The main symptoms observed in affected chickens included hepatitis-hydropericardium syndrome (HHS), stomach ulceration, and swollen bursa with bleeding spots, with detailed examinations showing significant organ damage.
- This study is the first to document DAdV-3's effects on chickens, demonstrating its capability to cause severe illness without any mutations in key viral regions post-infection.
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