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Perilymph sampling in Mongolian gerbil, technical note and procedure evaluation.
Hear Res
January 2025
CHU Lille, Department of Otology and Neurotology, F-59000 Lille, France; Univ. Lille, France; Univ. Lille, Inserm, CHU Lille, U1008, F-59000 Lille, France.
Objective: The aim of this study is to detail and evaluate the surgical procedure for perilymph sampling from the cochlear apex in the Mongolian gerbil.
Design: Perilymph sampling from the cochlear apex was performed one to three time in 12 male gerbils aged 8 to 12 months via the submandibular route. 11 of them were previously implanted with intracochlear implants loaded with dexamethasone and placed in the scala tympani, the 12th was used to collect control samples.
Technical Note: Self-Irrigation Device for Intraoral Home Care.
J Oral Maxillofac Surg
January 2025
Specialist, Department of Oral & Maxillofacial Surgery, Hospital Taiping, Taiping, Perak, Malaysia.
Following surgical treatment of a jaw cyst, bony cavities are formed. These cavities are prone to infection when they communicate with the oral environment. Hence, proper irrigation is a crucial aspect of postsurgical care, as it helps to reduce debris buildup and the risk of infection.
View Article and Find Full Text PDFLong-term outcome in people who use drugs successfully treated for hepatitis C infection with glecaprevir/pibrentasvir.
J Virus Erad
December 2024
Vancouver Infectious Diseases Center, Vancouver, British Columbia, Canada.
Background: Several clinical trials, including the recently published the GRAND PLAN study from Vancouver Infectious Diseases Center (VIDC), have demonstrated the efficacy of hepatitis C (HCV) therapy among active drug users, including those facing significant addiction-related and social challenges. In the GRAND PLAN, we documented sustained virological response post-treatment Week12 (SVR12) in 108/117 (92.3 %) individuals (108/111 (mITT) or 97.
View Article and Find Full Text PDFGender difference in domain-specific quality of life measured by modified WHOQoL-BREF questionnaire and their associated factors among older adults in a rural district in Bangladesh.
PLoS One
January 2025
School of Health Sciences, Swinburne University of Technology, Hawthorn, VIC, Australia.
Background: The global population of older adults has steadily increased in recent decades. Little is known about the gender difference in the quality of life (QoL) of older adults in the general population. This study aimed to identify factors associated with QoL among older adults by gender.
View Article and Find Full Text PDFThis study aimed to elucidate the impact of advanced glycation end products (AGEs) and glucose shock on cardiomyocyte viability, gene expression, cardiac biomarkers, and cardiac contractility. Firstly, AGEs were generated in-house, and their concentration was confirmed using absorbance measurements. AC16 cardiomyocytes were then exposed to varying doses of AGEs, resulting in dose-dependent decreases in cell viability.
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