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Antarmycins: Discovery, Biosynthesis, Anti-pathogenic Bacterial Activity, and Mechanism of Action from Deep-Sea-Derived .
JACS Au
January 2025
CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
The rapid emergence of antimicrobial-resistant pathogenic microbes has accelerated the search for novel therapeutic agents. Here we report the discovery of antarmycin A (), an antibiotic containing a symmetric 16-membered macrodiolide core with two pendant vancosamine moieties, one of which is glucosylated, from deep-sea-derived SCSIO 07407. The biosynthetic gene cluster of was identified on a giant plasmid featuring transferable elements.
View Article and Find Full Text PDFCliotide U1, a Novel Antimicrobial Peptide Isolated From Leaves.
Bioinform Biol Insights
January 2025
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Aims: Antibiotic resistance is currently a major challenge to scientists. Thus, attempts have been made to develop new compounds with antimicrobial activity. In this research, a new antimicrobial peptide with antibacterial activity was isolated from the plant .
View Article and Find Full Text PDFHydrogel inspired by "adobe" with antibacterial and antioxidant properties for diabetic wound healing.
Mater Today Bio
April 2025
Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.
With the aging population, the incidence of diabetes is increasing. Diabetes often leads to restricted neovascularization, antibiotic-resistant bacterial infections, reduced wound perfusion, and elevated reactive oxygen species, resulting in impaired microenvironments and prolonged wound healing. Hydrogels are important tissue engineering materials for wound healing, known for their high water content and good biocompatibility.
View Article and Find Full Text PDFInsights into the electronic, magnetic structure, and photocatalytic activity of YCuMnO double perovskite.
RSC Adv
January 2025
Department of Physics and Nanotechnology, Faculty of Engineering and Technology, SRM Institute of Science and Technology Kattankulathur Chennai Tamil Nadu 603203 India.
This research aims to develop YCuMnO double perovskite, using a citrate auto combustion method, to be used as a photocatalyst for the degradation of organic dyes and antibiotics. XRD and Raman characterization revealed the synthesis of pure-phase YCuMnO double perovskite. The X-ray photoelectron spectroscopy results show the presence of +4 and +2 oxidation states of Mn and Cu ions.
View Article and Find Full Text PDFGreen light-responsive photoelectrochemical sensing nanoplatform based on copper cobaltite nanorods for ultrasensitive detection of furazolidone antibiotic residue in food samples.
RSC Adv
January 2025
Phenikaa University Nano Institute (PHENA), PHENIKAA University Hanoi 12116 Vietnam
In this research, the preparation of copper cobaltite (CuCoO) nanorods and its potential application in photoelectrochemical sensing platform towards ultrasensitive detection of furazolidone are reported. X-ray diffraction, Raman spectra, scanning electron microscopy, and UV-visible spectroscopy have been performed to confirm the formation, morphology, phase composition, and optical properties of CuCoO synthesized by a microwave-assisted hydrothermal method. The electrochemical characteristic parameters were calculated electrochemical impedance spectroscopy, cyclic voltammetry, differential pulse voltammetry, and chronoamperometry techniques in the absence and presence of laser light irradiation.
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