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The Inflammatory Cytokine Imbalance for Miscarriage, Pregnancy Loss and COVID-19 Pneumonia.
Front Immunol
April 2022
Phytocal S.R.L., Rende (CS), Italy.
Pregnancy can be defined a vascular event upon endocrine control. In the human hemo-chorial placentation the chorionic villi penetrate the wall of the uterine spiral arteries, to provide increasing amounts of nutrients and oxygen for optimal fetal growth. In any physiological pregnancy the natural maternal response is of a Th1 inflammatory type, aimed at avoiding blood loss through the arteriolar wall openings.
View Article and Find Full Text PDFAim: The aim of the study was to evaluate the clinical usefulness of the selective removal of residual intrauterine trophoblastic tissue by using a hysteroscopic procedure, especially in the prevention of the Intra-Uterine Adhesion's Syndrome.
Methods: Seventy-six patients had an Asherman's Syndrome: 5 cases after laparotomic myomectomy, 1 after caesarean section, 2 after hysteroscopic myomectomy, 10 after VIP, 1 with a severe vaginal endometriosis, 1 after conisation, 4 after a post-partum hemorrhage due to coagulopathy or uterine atony, 20 cases after D&C because of PPH due to placental retention, 26 after repetitive D&Cs because of AUB due to post abortion chorial residues' retention, 6 cases after D&C for post menopausal AUB. Thirty-six patients presented AUB due to chorioplacental residues retention: 14 cases after a vaginal delivery or a caesarean section, 4 after VIP, 18 cases after repetitive D&Cs for incomplete or internal spontaneous abortion.
Placental enlargement in women with primary maternal cytomegalovirus infection is associated with fetal and neonatal disease.
Clin Infect Dis
October 2006
Department of Gynecological Sciences, Perinatology, and Child Health, La Sapienza University, Rome, Italy.
Background: Serological testing for primary maternal cytomegalovirus (CMV) infection during pregnancy is not routine, but ultrasound studies are routine. Therefore, we evaluated placental thickening in women with primary CMV infection during pregnancy.
Methods: The study included 92 women with primary CMV infection during pregnancy and 73 CMV-seropositive pregnant women without primary CMV infection.
Pathology of the trophoblast and fetal vessels of the placenta in maternal diabetes mellitus.
Acta Diabetol Lat
September 1977
The morphologic characteristics of the chorial villi from normal full-term placentas and from placentas of different clinical types of diabetic women were studied. The latter showed early maturation of the trophoblast, higher percentage of villi with stromal edema, and higher percentage of vessels of the villous trunks with lesions causing partial or total obstruction of the vascular lumen. The fact that the diabetic patients were treated suggests that the metabolic correction of diabetes mellitus prevents the occurrence or development of the multiple disturbances which the disease produces in the evolution of human pregnancy.
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