Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Improving the Accuracy of Diagnosis for Multiple-System Atrophy Using Deep Learning-Based Method.
Biology (Basel)
June 2022
Department of Neurology, Brain Research Institute, Niigata University, 1-757 Asahimachidori, Chuo-ku, Niigata City 951-8585, Japan.
Multiple-system atrophy (MSA) is primarily an autonomic disorder with parkinsonism or cerebellar ataxia. Clinical diagnosis of MSA at an early stage is challenging because the symptoms change over the course of the disease. Recently, various artificial intelligence-based programs have been developed to improve the diagnostic accuracy of neurodegenerative diseases, but most are limited to the evaluation of diagnostic imaging.
View Article and Find Full Text PDFAutonomic dysfunction following COVID-19 infection: an early experience.
Clin Auton Res
June 2021
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Purpose: Post-COVID-19 syndrome is a poorly understood aspect of the current pandemic, with clinical features that overlap with symptoms of autonomic/small fiber dysfunction. An early systematic analysis of autonomic dysfunction following COVID-19 is lacking and may provide initial insights into the spectrum of this condition.
Methods: We conducted a retrospective review of all patients with confirmed history of COVID-19 infection referred for autonomic testing for symptoms concerning for para-/postinfectious autonomic dysfunction at Mayo Clinic Rochester or Jacksonville between March 2020 and January 2021.
The Dual Nature of Onuf's Nucleus: Neuroanatomical Features and Peculiarities, in Health and Disease.
Front Neuroanat
September 2020
Department of Neuroscience Rita Levi Montalcini, University of Turin, Turin, Italy.
Article Synopsis
- Onuf's nucleus is a group of motor neurons in the sacral spinal cord that controls pelvic floor muscles and shares similarities with other motor neurons but also has some unique autonomic characteristics.
- The review discusses the specific histological and biochemical traits of Onuf's nucleus, as well as its involvement in various age-related and neurological disorders like Parkinson's disease and Shy-Drager Syndrome, while being unaffected by diseases like ALS and DMD.
- The article highlights key studies that have advanced our understanding of Onuf's neurons, emphasizing their vulnerability or resistance to damage, paving the way for potential new treatments for neurodegeneration.
Association of innervation-adjusted alpha-synuclein in arrector pili muscles with cardiac noradrenergic deficiency in autonomic synucleinopathies.
Clin Auton Res
December 2019
Autonomic Medicine Section (formerly Clinical Neurocardiology Section), Clinical Neurosciences Program, Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 9000 Rockville Pike MSC-1620, Building 10 Room 8N260, Bethesda, MD, 20892-1620, USA.
Background: Autonomic synucleinopathies feature deposition of the protein alpha-synuclein (AS) in neurons [e.g., Lewy body neurogenic orthostatic hypotension (nOH)] or glial cells (multiple system atrophy, MSA).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!