Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Here, BODIPY derivatives were functionalized with barbituric acid, which has multiple hydrogen bonding abilities that are directional, to have highly ordered hydrogen bond-mediated self-assembled structures to tune BODIPY's photophysical properties. The synthesis of barbituric acid-functionalized BODIPY derivatives via Vilsmeier and Knoevenagel reactions was achieved, and the resulting compounds were characterized with FT-IR, H NMR, C NMR spectroscopy, and mass spectrometry. Hydrogen bond-mediated self-assembled structures were investigated through UV-vis and fluorescence spectrophotometry, H NMR spectroscopy, and a dynamic light scattering method in solution.
View Article and Find Full Text PDFNew formyl indole derivatives based on thiobarbituric acid and their nano-formulations; synthesis, characterization, parasitology and histopathology investigations.
Sci Rep
January 2025
Chemistry Department, Faculty of Science, Alexandria University, P.O. Box 426, Alexandria, 21321, Egypt.
New formyl indole derivatives based on thiobarbituric acid were designed for targeting parasitological applications. The new compounds (5-((1H-indol-3-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione (3a), and 5-((1-benzyl-1H-indol-3-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione (3b) were synthesized as thioxodihydropyrimidine derivatives via aldol condensation reaction. The structures of the synthesized compounds were confirmed based on their spectral data via FT-IR, H and C NMR spectral characterization.
View Article and Find Full Text PDFCo-Treatment with Cranberry and Vitamin-C Mitigates Reproductive Toxicities Induced by Phenobarbital in Male Rats.
Cell Physiol Biochem
December 2024
Zoology Department, Faculty of Science, Tanta University, Tanta, Egypt.
Background/aims: Phenobarbital (PB), commonly used for epilepsy management, is associated with testicular dysfunction after prolonged use. This study aimed to evaluate the ameliorative effects of cranberry (CB) and vitamin C (Vit-C) on PB-induced reproductive toxicity in rats.
Methods: Forty male Wistar rats were divided into five groups.
Design and Synthesis of Novel Dual-Functional Protic Ionic Liquids with a Superior High CO Absorption Efficiency.
J Phys Chem B
January 2025
Collaborative Innovation Center of Chemical Science and Engineering, Tianjin University, Tianjin 300072, China.
As a predictive tool, quantum chemical calculations can be used to design protic ionic liquids (PILs) and predict the result. By adding anionic negative potential sites, two dual-functional PILs diethylenetriamine-barbituric acid [CHN][CHNO] and diethylenetriamine-ethylenolactonium [CHN][CHNO] were designed. The simulation results indicated that multisite absorption of anions and cations resulted in an expected absorption ratio exceeding 3:1 (mol CO:mol ILs).
View Article and Find Full Text PDFGrowth of Silver Nanoparticles into Reducing-End Carbohydrate-Based Supramolecular Hydrogels for Antimicrobial Applications.
ACS Appl Mater Interfaces
December 2024
Univ. Grenoble Alpes, CNRS, CERMAV, Grenoble 38000, France.
Hydrogels with antibacterial activities have the potential for many biomedical applications, such as wound healing, because of their capacity to maintain a moist environment and prevent infections. In this work, an ultrasound-induced supramolecular hydrogel consisting of easily accessible reducing-end-free glucosaminylbarbiturate-based hydrogelators that serve the fabrication of silver nanoparticles (AgNPs), excluding the addition of any external reducing or stabilizing agents, has been developed. The innovative synthetic approach relied on the use of -disubstituted barbituric acid derivatives as a versatile chemical platform that site-selectively reacted with the amino function of glucosamine.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!