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Limited research has explored histamine intolerance from the perspective of primary caregivers. Our objective was to develop a practical symptom profile from the standpoint of general practice. We also aimed to gather data on the frequency and timing of disease progression and to establish a staging system.

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Introduction: Taxane medications, paclitaxel, and docetaxel, are chemotherapy agents that have a higher incidence of reported hypersensitivity and infusion reactions. To help classify these reactions, the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) is utilized. Prophylactic medications have been used to decrease the incidence and severity of these events.

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Objective: Chronic spontaneous urticaria (CSU) is a challenging condition that significantly impacts the affected patients. This study aimed to evaluate the quality of life (QoL) among patients with CSU in Vietnam and identify factors associated with QoL.

Methods: A cross-sectional study was conducted at the Vietnam National Dermatology and Venereology Hospital from June 2023 to March 2024.

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Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects.

Trends Mol Med

January 2025

Millennium Institute of Immunology and Immunotherapy, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile; Departamento de Endocrinología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Electronic address:

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder that represents a significant public health challenge worldwide. This multifactorial condition results from complex interactions among genetic, environmental, immune, and microbial factors. Some beneficial microbes, known as probiotics, have been identified as promising therapeutic agents for inflammatory conditions, such as IBD.

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Potassium Current Signature of Neuronal/Glial Progenitors in Amniotic Fluid Stem Cells.

Cells

January 2025

Department of Chemistry, Biology and Biotechnologies, University of Perugia, Via dell'Elce di Sotto 8, 06123 Perugia, Italy.

Article Synopsis
  • Amniotic fluid contains stem cells (AF-SCs) that have potential uses in regenerative medicine for treating various injuries and diseases.
  • When exposed to basic Fibroblast Growth Factor (bFGF), AF-SCs show the ability to survive and migrate in a rat brain model, resembling characteristics of neuronal/glial progenitor cells.
  • The study employs electrophysiological techniques to identify specific potassium currents in AF-SCs and confirms that histamine can influence calcium dynamics and potassium current activation in these cells.
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