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Synthetic MR: Clinical applications in neuroradiology.
Neuroradiology
January 2025
Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, 695011, Kerala, India.
Purpose: Synthetic MR is a quantitative MRI method that measures tissue relaxation times and generates multiple contrast-weighted images using suitable algorithms. The present article principally discusses the multiple dynamic multiple echo (MDME) technique of synthetic MR and briefly describes other quantitative MR sequences.
Methods: Using illustrative cases, various applications of the MDME sequence in neuroradiology are explained.
Predicting human olfactory perception by odorant structure and receptor activation profile.
Chem Senses
January 2025
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Humans possess a remarkable ability to discriminate a wide range of odors with high precision. This process begins with olfactory receptors (ORs) detecting and responding to the molecular structures of odorants. Recent studies have aimed to associate the activity of a single OR to an odor descriptor or predict odor descriptors using 2D molecular representation.
View Article and Find Full Text PDF[Direct Surgery for Spinal Arteriovenous Shunt Disease: Indication and Technical Tips].
No Shinkei Geka
January 2025
Department of Neurological Surgery, Okayama University Graduate School of Medicine.
Spinal arteriovenous(AV) shunt disease is rare, although many neurosurgeons may encounter patients with the disease. Recently, the pathological findings and classification of spinal AV shunt disease have been well described. The fundamental treatment of spinal AV shunt disease involves interruption of the shunt, which is achieved by endovascular treatment or direct surgery.
View Article and Find Full Text PDFPhase separation of EEF1E1 promotes tumor stemness via PTEN/AKT-mediated DNA repair in hepatocellular carcinoma.
Cancer Lett
January 2025
Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address:
This study aimed to investigate the associations of liquid-liquid phase separation (LLPS) and tumor stemness in hepatocellular carcinomas (HCC). LLPS-related genes were extracted from DrLLPS, LLPSDB and PhaSepDB databases. Stemness index (mRNAsi) was calculated based on the data from TCGA and Progenitor Cell Biology Consortium.
View Article and Find Full Text PDFOn some integral inequalities of Grüss type involving the generalized fractional Saigo -integral operator.
Heliyon
January 2025
Department of Mathematics, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu 602105, India.
Using the generalized Saigo fractional integral operator, the authors of this study prove several novel fractional integral inequalities of the Grüss type. By fixing the values of functions, specific situations derived from previously established findings are shown. The ultimate purpose of this work is to investigate the Grüss-type integral inequalities with the Saigo -integral operator, a more generalized integral operator.
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