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From the Cytoplasm into the Nucleus-Hepatitis B Virus Travel and Genome Repair.
Microorganisms
January 2025
Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 41346 Gothenburg, Sweden.
Hepatitis B virus (HBV) is a major global health concern, affecting millions of people worldwide. HBV is part of the hepadnaviridae family and one of the primary causes of acute and chronic liver infections, leading to conditions such as cirrhosis and hepatocellular carcinoma (HCC). Understanding the intracellular transport and genome repair mechanisms of HBV is crucial for developing new drugs, which-in combination with immune modulators-may contribute to potential cures.
View Article and Find Full Text PDFHepatitis Secondary to an Over-the-Counter Appetite Stimulant: A Case Report.
Cureus
November 2024
Pediatric Gastroenterology, Columbia University, New York, USA.
We present the case of a previously healthy 11-year-old boy who developed hepatitis in the setting of regular intake of Apetamin. Apetamin is an appetite stimulant not approved by the United States Food and Drug Administration that contains cyproheptadine, lysine, and multiple B vitamins. It is illegally imported into the United States and can be purchased online.
View Article and Find Full Text PDFCase report: Malaria and hepatitis E coinfection-first experience with such imported entity in Serbia.
Front Med (Lausanne)
December 2024
Department of Infectious Diseases and Epidemiology, Faculty of Medicine, University of Niš, Niš, Serbia.
Acute hepatitis E virus (HEV) and malaria are not rare infections in tropical countries; however, in the European continent, such imported entity has not been reported up to now. Herein, we report a 24-year-old male suffering from malaria and hepatitis E, who was admitted with acute hepatic failure dark colored urine, followed by coagulation and inflammation parameters increase. Blood smear analysis revealed the presence of , while serological tests revealed anti-HEV IgM antibodies.
View Article and Find Full Text PDFThe epidemiology of notifiable diseases in Australia and the impact of the COVID-19 pandemic, 2012-2022.
BMC Glob Public Health
January 2024
School of Public Health and Preventive Medicine, Monash University, 553 St Kilda Road, Melbourne, VIC, 3004, Australia.
Background: Infectious disease surveillance tracks disease epidemiology and informs prevention and control. Public health measures implemented in Australia during the COVID-19 pandemic (2020 to 2022) affected infectious disease epidemiology. We examined notifiable disease epidemiology in Australia from 2012 to 2022, evaluating disease trends and pandemic impacts.
View Article and Find Full Text PDFEstimating the prevalence of chronic infections among asymptomatic migrants: results of a screening programme in Catalonia, Spain.
J Migr Health
October 2024
Barcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona. Carrer Roselló 132, 08036 Barcelona, Spain.
Background: Migrants are disproportionately affected by several infectious diseases differing the risk within migrant groups. This study aimed to estimate the prevalence of six chronic infections in asymptomatic migrants attended at primary care or specialized units where health assessments are offered.
Methods: A multicentric cross-sectional study was conducted to estimate the prevalence of human immunodeficiency virus (HIV), hepatitis B and C virus, spp, and infections in the migrant population who participated in a screening programme implemented at six primary health care centres, and two infectious diseases outpatient clinics in Catalonia, Spain.
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