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Unlabelled: Right-to-left shunt may be a cause of paradoxical embolization (and cryptogenic cerebral ischemic events). Patent foramen ovale and pulmonary arterio-venous malformations are the most common cause of paradoxical embolization; however, some rare cardiovascular lesions may cause a right-to-left shunt with consequent paradoxical embolization. We describe a case of a young child with superior sinus venosus atrial septal defect who underwent surgical closure and developed a cryptogenic cerebral ischemic attack due to a rare cause of paradoxical embolization, during a long-term follow-up.

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Presentation, Treatment and Outcomes of Brachial Artery Aneurysms.

J Vasc Surg

January 2025

Department of Cardiovascular Surgery, Mayo Clinic Health System, Eau Claire, WI. Electronic address:

Objective: Brachial artery aneurysms are rare entities that have typically been associated with trauma, infection, arterio-venous fistula creation or connective tissue disorders. These aneurysms are often asymptomatic, but they can also cause local tenderness or thrombo-embolic events. Due to the very low incidence of true brachial artery aneurysms, there are no standardized guidelines on their optimal management.

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Introduction: Rates of morbidity and mortality are high in the setting of Fontan physiology and effective medical therapies are not well-established. Clinical trials assessing phosophodiesterase-5-inhibitors, such as sildenafil, have not demonstrated major benefit in patients with a Fontan-type circulation but have only included stable, well-functioning people.

Methods: We sought to retrospectively characterize the people followed by the ANZ Fontan Registry prescribed sildenafil >30 days post Fontan-surgery.

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Left atrial veno-arterial extracorporeal membrane oxygenation (LAVA-ECMO) in cardiogenic shock (CS) is a novel mechanical cardiocirculatory support strategy that provides robust cardiocirculatory support and simultaneous left and right atrial venting by way of a multifenestrated transeptal catheter. We performed a single-center retrospective analysis of all patients aged ≥18 years with CS who underwent LAVA-ECMO at a quaternary care institution from 2018 to 2023. Clinical outcomes and prehemodynamics and posthemodynamics were evaluated.

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Diabetic Charcot neuroarthropathy: A threat to both limb and life.

Diabetes Obes Metab

January 2025

Midstate Endocrine Associates, Lipscomb University, Nashville, Tennessee, USA.

Article Synopsis
  • Diabetic Charcot neuroarthropathy (DCN) is a rare but serious complication of diabetes, particularly affecting those with diabetic neuropathy, where the incidence rises to 30%, especially among type 1 diabetics.
  • It typically presents as a painless, swollen, and warm foot or ankle, with MRI and X-ray revealing specific joint abnormalities, often in a particular order.
  • Treatment primarily involves prolonged immobilization and offloading, with potential but unproven therapeutic options; there's a high risk of amputation and increased mortality, especially when foot ulcers are present, necessitating surgical intervention to prevent recurrence.
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