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Bio-nanopore technology for biomolecules detection.
Adv Biotechnol (Singap)
December 2024
School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, 214122, Jiangsu, China.
Bio-nanopore technology holds great promise in biomacromolecule detection, with its high throughput and low cost positioning it as an ideal detection tool. This technology employs a unique detection mechanism that utilizes nanoscale pores to rapidly and sensitively convert biological molecules interactions into electrical signals, enabling real-time, single-molecule detection with exceptional sensitivity. This review focuses on the latest advancements in this technology across various domains, including DNA and RNA sequencing, protein detection, and small molecule identification.
View Article and Find Full Text PDFA review of recent advancements in the impact response of fiber metal laminates.
Heliyon
January 2025
Natural Composites Research Group Lab, Department of Materials and Production Engineering, The Sirindhorn International Thai-German School of Engineering (TGGS), King Mongkut's University of Technology North Bangkok (KMUTNB), Bangkok, 10800, Thailand.
Fiber metal laminates (FMLs) have garnered significant attention due to their exceptional impact resistance, making them attractive for various structural applications. This review presents recent advancements in understanding the impact behavior of FMLs under low- and high-velocity impact scenarios. Low-velocity impacts, commonly encountered during manufacturing, handling, and tool drops, are discussed, with a focus on damage mechanisms, energy absorption capabilities, and influential factors such as impactor geometry and boundary conditions.
View Article and Find Full Text PDFIntegration of ratiometric, ultrafast, sensitive detection as well as rapid and efficient removal of tetracycline based on a novel Zn (II) functionalized magnetic covalent organic framework.
Anal Chim Acta
March 2025
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, PR China. Electronic address:
Background: Based on the low volatility and refractory nature of Tetracycline (TC), excessive use leads to its continuous accumulation in water environments, posing serious risks to the ecological environment and human health. Although a very limited number of nanomaterials capable of simultaneously detecting and removing TC have been fabricated, they generally exist issues associated with a single detection signal ("on" or "off") or low adsorption rates with low adsorption capacities. As a result, it is crucial to develop a reliable technique to achieve ratiometric detection as well as rapid and efficient removal of TC.
View Article and Find Full Text PDFMitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation.
Biomaterials
January 2025
Chongqing Key Laboratory of Reproductive Health and Digital Medicine, Department of Laboratory Medicine, Chongqing General Hospital, School of Medicine, Chongqing University, Chongqing, 400044, People's Republic of China; College of Life Science and Laboratory Medicine, Kunming Medical University, Kunming, Yunnan, 650050, People's Republic of China. Electronic address:
Ischemia/reperfusion injury (I/RI) following myocardial infarction, a leading cause of global morbidity and mortality, is characterized by detrimental oxidative stress and inflammation. In response, we proposed an I/RI alleviation strategy using the intravenous injection of spherical selenium nanoparticles (SeNPs) synthesized by a template method. Single-cell sequencing revealed these proposed SeNPs exhibited exceptional antioxidant and anti-inflammatory properties, disrupting the STAT1-ROS cycle, therefore preserving mitochondrial respiration and inhibiting caspase-mediated cardiomyocyte apoptosis.
View Article and Find Full Text PDFA numerical approach to model and analyse geometric characteristics of a grey-headed albatross aerofoil in flight.
Bioinspir Biomim
January 2025
Department of Mechanical and Aeronautical Engineering, University of Pretoria, University of Pretoria, Pretoria, 0002, SOUTH AFRICA.
Limited research exists on the 3D geometric models and aerodynamic characteristics of the Grey-headed Albatross (GHA). Despite existing methods for extracting bird wing cross-sections, few studies consider deflections due to aerodynamic pressure. With the GHA known for its exceptional flight speed and purported wing-lock mechanism, it offers a valuable subject for studying fixed-wing aerodynamicsin nature.
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