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Recurrent acute pancreatitis in pediatrics: characteristics and risk factors.
Arch Argent Pediatr
January 2025
Pediatric Gastroenterology Service, Hospital Nacional Profesor Alejandro Posadas, El Palomar, Argentina.
Recurrent acute pancreatitis (RAP) affects 15-36% of children with acute pancreatitis (AP) and may progress to chronicity. To determine the etiology and evolution of RAP, a descriptive retrospective cohort study was conducted in patients aged 1-18 years. Twelve patients with RAP were included out of 79 with AP, and demographic, etiological, clinical, analytical, and imaging data were collected.
View Article and Find Full Text PDFNPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment.
FEBS Open Bio
December 2024
Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Hepatocellular carcinoma remains a significant threat to human health. Recent studies have found that the intake of cellular cholesterol contributes to the development and progression of hepatocellular carcinoma, although the exact mechanisms remain unclear. Our analysis of transcriptomic and proteomic databases has identified increased mRNA and protein expression levels of NPC1, a cholesterol intracellular transporter protein, in hepatocellular carcinoma tissues.
View Article and Find Full Text PDFCorrelation between endoscopic ultrasound features and exocrine pancreatic function in chronic pancreatitis.
Pancreatology
September 2024
Pancreato-Biliary Endoscopy and Endosonography Division, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita-Salute San Raffaele University, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy. Electronic address:
Background: Endoscopic ultrasound (EUS) is the most sensitive method for diagnosing chronic pancreatitis (CP) in its early stages, and Rosemont Classification (RC) is used for its evaluation. Data on the correlation between EUS features and pancreatic exocrine insufficiency (PEI) are limited. We investigated the correlation between the EUS findings and PEI.
View Article and Find Full Text PDFSuccessful treatment of feline pancreatolithiasis associated with an ascending Providencia rettgeri infection using a novel surgical technique.
Aust Vet J
September 2024
Cat Specialist Services, Underwood, Queensland, Australia.
A 12-year-old female spayed Domestic Shorthair cat presented with a 4-day history of lethargy, inappetence and vomiting. Physical findings included a grade 2/6 heart murmur and cranial abdominal pain on palpation. Serum biochemistry revealed elevated total bilirubin and liver enzymes activities.
View Article and Find Full Text PDFPoorly Controlled New-Onset Diabetes Mellitus and Other Atypical Signs as an Early Sign of Pancreatic Adenocarcinoma.
Cureus
June 2024
Department of Gastroenterology, Complejo Asistencial de Zamora, Zamora, ESP.
Article Synopsis
- - A 50-year-old man was diagnosed with new-onset diabetes and later developed severe abdominal pain and vomiting, leading to the discovery of acute pancreatitis through an abdominal CT scan.
- - Despite ruling out common causes like gallstones and toxic factors, his condition worsened, showing signs of necrotic tissue and portal vein thrombosis over time.
- - Further tests indicated a possible hidden cancer, and analysis of the fluid around his abdomen confirmed pancreatic adenocarcinoma, but unfortunately, he passed away a year after his initial diagnosis.
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