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Protocol for the systematic review of age and sex in preclinical models of age-correlated diseases.
F1000Res
January 2025
German Centre for the Protection of Laboratory Animals (Bf3R), German Federal Institute for Risk Assessment (BfR), Berlin, Berlin, Germany.
The translation of animal-based biomedical research into clinical research is often inadequate. Maximizing translation should be central to animal research on human diseases, guiding researchers in study design and animal model selection. However, practical considerations often drive the choice of animal model, which may not always reflect key patient characteristics, such as sex and age, impacting the disease's course.
View Article and Find Full Text PDFInfant and young child feeding practice status and its determinants in UAE: results from the MISC cohort.
Int Breastfeed J
January 2025
Department of Clinical Nutrition and Dietetics, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Background: To evaluate breastfeeding and complementary feeding practices and their determinants among infants and young children in the United Arab Emirates using the 2021 WHO/UNICEF IYCF guidelines.
Methods: The Mother and Infant Study Cohort (MISC), is a prospective study of mothers recruited in their third gestational trimester and followed with their infants up to 18 months of age (n = 167). Data were collected at 3rd trimester, delivery, 2, 6, 12, and 18 months postpartum via questionnaires, review of medical records, anthropometric measurements, and 24-hour dietary recalls of the child's intake at 6, 12, and 18 months.
Pilot study of a ketogenic diet in bipolar disorder: a process evaluation.
BMC Psychiatry
January 2025
MRC/CSO Social and Public Health Sciences Unit, School of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Background: Bipolar disorder is a serious mental illness, which requires new strategies for prevention and management. Recent evidence suggests that a ketogenic diet may be an effective intervention. This research aimed to explore the feasibility and acceptability of a ketogenic diet intervention for bipolar disorder, fidelity to its behavioural components and the experiences of the participants and research clinicians involved.
View Article and Find Full Text PDFColostrum avoidance and associated factors among postnatal mothers in health facilities in Addis Ababa, Ethiopia: a mixed method study.
BMC Public Health
January 2025
School of Public Health, St Paul's Hospital Millennium Medical College, Addis Ababa City Administration, P.O. Box 1271, Addis Ababa, Ethiopia.
Background: Colostrum is the first form of milk produced immediately following the delivery of a newborn. It is highly nutritious and contains antibodies to protect the newborn against disease and crucial for the newborn's health Despite its benefits, some mothers avoid giving colostrum to their newborns.
Objective: This study aims to assess the prevalence and factors associated with colostrum avoidance among postnatal mothers in Addis Ababa, Ethiopia.
Over a decade of HIV infection prevalence and incidence among Mozambican pregnant women: a secondary analysis of prospectively collected data.
BMC Public Health
January 2025
Centro de Investigação Em Saúde de Manhiça (CISM), Rua 12, Maputo, Vila da Manhiça, PO Box 1929, Mozambique.
Background: Monitoring HIV infection estimates is critical to guide health interventions and assess their impact, especially in highly vulnerable groups to the infection such as African pregnant women. This study describes the trends of HIV infection over eleven years in women attending selected antenatal care (ANC) clinics from southern Mozambique.
Methods: We performed a secondary analysis of data registered at the ANC clinic of the Manhiça District Hospital and from the Ministry of Health's HIV National Program Registry between 2010 and 2021.
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