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Unlabelled: While visual working memory (WM) is strongly associated with reductions in occipitoparietal 8-12 Hz alpha power, the role of 4-7 Hz frontal midline theta power is less clear, with both increases and decreases widely reported. Here, we test the hypothesis that this theta paradox can be explained by non-oscillatory, aperiodic neural activity dynamics. Because traditional time-frequency analyses of electroencephalopgraphy (EEG) data conflate oscillations and aperiodic activity, event-related changes in aperiodic activity can manifest as task-related changes in apparent oscillations, even when none are present.
View Article and Find Full Text PDFContinuous quantitative electroencephalography for early detection of acute low-pressure obstructive hydrocephalus in aneurysmal subarachnoid hemorrhage: illustrative case.
J Neurosurg Case Lessons
December 2024
Department of Medicine, Neuroscience Intensive Care Unit, Medical Critical Care Service, INOVA Fairfax Hospital, Falls Church, Virginia.
Background: Aneurysmal subarachnoid hemorrhage (aSAH) is often associated with acute high-pressure hydrocephalus. Less commonly, an acute low-pressure hydrocephalus (ALPH) variant can develop and contribute to increased morbidity. ALPH is particularly challenging to diagnose and manage, as patients present with symptoms of increased intracranial pressure (ICP) despite the absence of corroborating evidence from ICP measurements.
View Article and Find Full Text PDFContinuous theta burst stimulation at 30 hz does not modulate cortical excitability in a sham-controlled study.
Sci Rep
December 2024
REVAL - Rehabilitation Research Center, Faculty of Rehabilitation Sciences, University of Hasselt - Campus Diepenbeek, Wetenschapspark 7, Diepenbeek, B-3590, Belgium.
Theta burst stimulation (TBS) can modulate cortical excitability but suffers from high inter-subject variability. Modified TBS frequency patterns (30 Hz) showed consistent inhibitory aftereffects, but further research into the time course of these effects is needed. This study aimed to investigate the efficacy of a 30 Hz continuous TBS (cTBS) protocol.
View Article and Find Full Text PDF[Not Available].
Ugeskr Laeger
November 2024
Hjerteafdeling Y, Københavns Universitetshospital - Bispebjerg og Frederiksberg Hospital.
Article Synopsis
- * A case study is presented involving a 68-year-old woman with hippocampal sclerosis who experienced IA and mesial temporal lobe epilepsy.
- * There's limited evidence linking IB/IA to sudden unexpected death in epilepsy, and pacemaker treatment is not commonly used; the focus of care is primarily on reducing seizures and preventing falls.
Fluoxetine does not influence response to continuous theta burst stimulation in human motor cortex.
Neuropsychopharmacol Rep
March 2025
University College London, London, UK.
Aim: Selective serotonin reuptake inhibitors are thought to exert a clinical effect through various mechanisms, including through alteration in synaptic plasticity. Repetitive transcranial magnetic stimulation can induce temporary changes in synaptic excitability in cerebral cortex that resemble long-term potentiation and long-term depression that serve as a measure of synaptic plasticity in vivo. A version of repetitive transcranial magnetic stimulation called continuous theta burst stimulation can induce inhibition of cortical excitability that can be measured through a motor evoked potential.
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