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Lanolin.
Dermatitis
March 2023
From the Department of Dermatology, Columbia University Irving Medical Center, New York, New York, USA.
Lanolin is a complex mixture of high molecular weight esters, aliphatic alcohols, sterols, fatty acids, and hydrocarbons that has been widely used for centuries for its emollient properties. The purification of crude lanolin into lanolin wax and the processing of this wax into various derivatives began in 1882 and continue to this day with newer highly purified anhydrous lanolins. Controversy as to lanolin's allergenicity began in the 1920s and remains an issue.
View Article and Find Full Text PDFMulti-residue analysis of certain lanolin nipple care products for trace contaminants.
BMC Chem
February 2023
Lansinoh Laboratories, Leeds, UK.
Background: Topical lanolin is commonly used on nipples to aid breastfeeding success. The raw material undergoes refinement to remove contaminants such as pesticides, which may accumulate from exogenous environmental sources. The level of refinement influences final lanolin purity.
View Article and Find Full Text PDFDevelopment and validation of multiresidue method for organophosphorus pesticides in lanolin using gas chromatography-tandem mass spectrometry.
J Mass Spectrom
November 2022
Department of Food Technology, School of Interdisciplinary Sciences, Jamia Hamdard, New Delhi, 110062, India.
Lanolin, also known as wool wax, is derived from sheep and has diverse applications in food, cosmetic, textile and lubricant industries. Owing to its direct contact with human, there is a need of studying pesticide residues as contaminants in lanolin. The present study describes a single novel hyphenated gas chromatography-tandem mass spectrometry (GC-MS/MS) technique for the quantification of 14 organophosphorus (OP) pesticides (tecnazene, propetamphos, diazinon, dichlofenthion, chlorpyrifos methyl, fenchlorphos, malathion, chlorpyrifos, pirimiphos ethyl, bromophos ethyl, tetrachlorvinphos, ethion, phosalone, and coumaphos) in lanolin using electrospray ionization (EI) with multiple reaction monitoring (MRM) acquisition mode.
View Article and Find Full Text PDFIsolation of lanosterol and dihydrolanosterol from the unsaponifiable matter of lanolin by urea complexation and countercurrent chromatography in heart-cut recycling mode.
J Chromatogr B Analyt Technol Biomed Life Sci
November 2022
University of Hohenheim, Institute of Food Chemistry, Department of Food Chemistry (170b), Garbenstraße 28, D-70599 Stuttgart, Germany. Electronic address:
4,4-Dimethyl-substituted sterols are bioactive minor sterols of most animal fats and plant oils, but higher shares are present in lanolin (wool grease). Here, the isolation of the 4,4-dimethyl-substituted sterols dihydrolanosterol and lanosterol from lanolin by countercurrent chromatography (CCC) is described. An initial examination of the hexane extract of saponified lanolin showed the presence of relatively high portions of fatty alcohols which were known to co-elute with the target analytes in CCC.
View Article and Find Full Text PDFPediatric contact dermatitis: what's new.
Curr Opin Pediatr
August 2020
Department of Dermatology, Massachusetts General Hospital.
Purpose Of Review: Allergic contact dermatitis (ACD) was once thought to be rare in children but recent studies have demonstrated that the prevalence of ACD is common and appears to be increasing in children. Current trends including toys, hobbies, and personal care products may play a role in potentially new allergen exposure or resurgence of certain allergens, making ACD a moving target in children.
Recent Findings: ACD and atopic dermatitis can coexist and certain clinical features can help differentiate ACD from endogenous atopic dermatitis in children.
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