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Radiosurgical pathology of brain tumors: metastases, schwannomas, meningiomas, astrocytomas, hemangioblastomas.
Prog Neurol Surg
July 2007
National Institute of Neurosurgery and Department of Neurological Surgery, Semmelweis University, Budapest, Hungary.
Systematic human pathological background to brain tumor radiosurgery explaining biological and pathophysiological effects of focused irradiation barely exists. The goal of this study was to explore histopathological changes evoked by single high-dose irradiation in a set of different brain tumors following Gamma Knife radiosurgery (GKRS). Light microscopy revealed that GKRS evokes degenerative and proliferative pathological changes in the parenchyma, stroma and vessels of the irradiated tumors.
View Article and Find Full Text PDFIrradiation lesions of the hip are much better known than they used to be, and problems diagnosis no longer arise. Study of these 49 cases of irradiation lesions of the hip shows that they occur in 1 to 36 per cent of patients irradiated for pelvic cancer. The rate of occurrence may be reduced by selection and improvement in the techniques of radiotherapy.
View Article and Find Full Text PDF[Surgical management of left colon and rectal radiation injuries (author's transl)].
J Chir (Paris)
December 1977
A. First of all, we can affirm after the analysis of 132 records: the predominance of gynecologic cancers and the frequent responsibility of medical associations in the determinism of advanced radiation injuries of colon and rectum; the typically variable appearence of these injuries with an usual delay going from 6 months to a year and limits from 2 months to 35 years; the difficulty of diagnosis between radiation injurie and recurrence of cancer especially in case of fistula and the severe forecost in case of cancer radiation injurie association. B.
View Article and Find Full Text PDFWith the increasing number of high-energy irradiation sources, the cases of radiolesions of the CNS are also increasing. The irradiation effects on nerve and tumour tissue and the various kinds of irradiation damage are discussed. They become manifest as (a) acute radionecrosis (rare) and (b) late reactions which are subdivided into delayed lesions and the more frequently occurring late necrosis proper.
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