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Parents of children with special needs are more likely to experience stress and have health-related problems. Pediatric occupational therapy interventions that build parents' capacity are often considered to be effective. It remains unclear how they can be offered without overburdening parents.
View Article and Find Full Text PDFEnhancing education for children with ASD: a review of evaluation and measurement in AI tool implementation.
Disabil Rehabil Assist Technol
March 2025
Department of Chemical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia.
This article addresses the gaps in current research regarding the use of artificial intelligence (AI) tools to educate children with autism spectrum disorder (ASD). The proposed metrics are specifically designed to evaluate the progress of learning in AI-assisted education, considering the unique needs of this demographic. The review highlights the potential of long-term impact studies to determine the lasting effects of AI on social skills, emotional development, and overall academic achievement.
View Article and Find Full Text PDFHalogen-substituted benzylamine crown ether inclusion complexes.
Acta Crystallogr C Struct Chem
April 2025
Ordered Matter Science Research Center, Nanchang University, Nanchang 330031, People's Republic of China.
Noncovalent interactions have received much attention in the fields of supramolecular chemistry and crystal engineering. Hydrogen bonding and weak interaction forces affect crystal stacking. Crown-ether-based host-guest inclusion compounds with hydrogen bonding and weak intermolecular interaction forces deserve our attention.
View Article and Find Full Text PDFDesign, synthesis, and biological evaluation of novel derivatives of marine natural product ammosamide B.
Pest Manag Sci
March 2025
Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin, China.
Background: Plant diseases caused by plant viruses and pathogens seriously affect crop yield and quality, making prevention and control extremely difficult and posing a serious threat to human health. Marine alkaloids have novel structures and diverse biological activities, which are an important source of the development of new pesticides. In this work, ammosamide alkaloids were selected as the parent structure.
View Article and Find Full Text PDFHow a patient-led advocacy organization supports the road to diagnosis and treatment of creatine transporter deficiency.
Front Neurosci
February 2025
Association for Creatine Deficiencies, Carlsbad, CA, United States.
The current era of drug development has evolved significantly. Patient advocacy organizations are moving beyond simply supporting community members and are taking the reins to improve the speed of diagnoses, initiate therapeutic discoveries, and lay the groundwork to ensure successful clinical trials. The Association for Creatine Deficiencies (ACD) is an international parent-led patient advocacy organization focused on the three ultra-rare neurodevelopmental monogenic disorders resulting in Cerebral Creatine Deficiency Syndromes (CCDS).
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