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Objectives: Geotrichum spp can be responsible for severe infections in immunocompromised patients. We aim to describe Geotrichum-related infections in the ICU and to assess risk factors of mortality.

Methods: Retrospective multicentre study, conducted in 14 French ICUs between 2002 and 2018, including critically ill adult patients with proven or probable infection related to Geotrichum species.

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Fungi are a versatile group of microorganisms that exist in three morphological forms, which include the yeasts (oval/spherical budding cells), true fungi (produce long filamentous, branching structures called as hyphae/mycelia), and dimorphic fungi (show both yeast at 37C and hyphal forms at room temperature). Most fungi are present in the environment and live as saprophytes. Some fungal species like the are present in the human respiratory, intestinal, and genitourinary tract as commensals.

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Cutaneous geotrichosis due to in a burn patient.

Access Microbiol

March 2019

Division of Infectious Diseases, Department of Internal Medicine, Wayne State University, Detroit, MI, USA.

is a saprophytic yeast known to colonize the human skin, respiratory tract and gastrointestinal tract. It can cause local or disseminated disease (geotrichosis), mainly in the immunocompromised host. Trauma, indwelling catheter use, prolonged broad-spectrum antibiotic treatment and critical illness have also been implicated as risk factors.

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Introduction: Geotrichum capitatum sepsis are rare, occurring exclusively in immunocompromised patients.

Exegesis: We report the case of a patient with acute leukemia, presenting with chemotherapy-induced neutropenia and hospitalized in an intensive care unit for a severe sepsis. In spite of an antibiotic and antifungal treatment, the patient died of cardiorespiratory failure.

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