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Chin Med J (Engl)
January 2025
Department of Surgery, University of Virginia, Charlottesville, Virginia 22903, USA.
Am J Cardiovasc Drugs
January 2025
Springer Nature, Private Bag 65901, Mairangi Bay, Auckland, 0754, New Zealand.
Flurpiridaz F 18 (FLYRCADO™) is an intravenous (IV) radioactive diagnostic drug being developed by GE Healthcare and Lantheus Medical Imaging for use in positron emission tomography (PET) myocardial perfusion imaging (MPI) to detect coronary artery disease (CAD). In September 2024, flurpiridaz F 18 was approved in the USA for PET MPI under rest or stress (pharmacologic or exercise) in adult patients with known or suspected CAD to evaluate for myocardial ischemia and infarction. This article summarizes the milestones in the development of flurpiridaz F 18 leading to this first approval for use in PET MPI in adult patients to evaluate for myocardial ischemia and infarction.
View Article and Find Full Text PDFPharmaceuticals (Basel)
December 2024
Dipartimento di Scienze della Vita, della Salute e delle Professioni Sanitarie, Università degli Studi "Link Campus University", Via del Casale di S. Pio V 44, I-00165 Rome, Italy.
, , and parasites are responsible for infectious diseases threatening millions of people worldwide. Despite more recent efforts devoted to the search for new antiprotozoal agents, efficacy, safety, and resistance issues still hinder the development of suited therapeutic options. The lack of robustly validated targets and the complexity of parasite's diseases have made phenotypic screening a preferential drug discovery strategy for the identification of new chemical entities.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Faculty of Information Science and Technology, Hokkaido University, N-14, W-9, Kita-ku, Sapporo 060-0814, Hokkaido, Japan.
In sports training, personalized skill assessment and feedback are crucial for athletes to master complex movements and improve performance. However, existing research on skill transfer predominantly focuses on skill evaluation through video analysis, addressing only a single facet of the multifaceted process required for skill acquisition. Furthermore, in the limited studies that generate expert comments, the learner's skill level is predetermined, and the spatial-temporal information of human movement is often overlooked.
View Article and Find Full Text PDFJ Clin Med
January 2025
Otorhinolaryngology and Head and Neck Surgery Department, University Medical Centre Utrecht, PB 85500, 3508 GA Utrecht, The Netherlands.
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