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Infection Reducing Strategies in Sacroneuromodulation: A Systematic Review.

Neurourol Urodyn

February 2025

Division of Urogynecology and Reconstructive Pelvic Surgery, University of Louisville, Louisville, Kentucky, USA.

Objectives: To determine the effect of infection-reducing strategies on postoperative complications for adult patients receiving sacroneuromodulation (SNM).

Methods: A systematic search of PubMed, Web of Science, Embase, Ovid, various EBSCOHost databases, and ClinicalTrials.gov was initially performed on December 21, 2023, and updated on March 25, 2024.

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[Perioperative antibiotic prophylaxis in obesity].

Orthopadie (Heidelb)

February 2025

St. Vinzenz-Krankenhaus Düsseldorf, Schloßstraße 85, 40477, Düsseldorf, Deutschland.

Background: In terms of perioperative infections, arthroplasty for obese patients represents a high-risk procedure. Correct antibiotic prophylaxis is a central pillar of infection prophylaxis. Studies showed increased infection rates if an antibiotic other than cefazolin was administered for prophylaxis.

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In recent years, the Japanese neurosurgical field has been added to the guidelines for the appropriate use of antimicrobial agents for the prevention of surgical site infection; however, the awareness of neurosurgeons and specific methods for surgical site infection prevention in the Japanese neurosurgical field remains unclear. Therefore, we report a repeat survey conducted after the addition of guidelines on the appropriate use of antimicrobial agents for the prevention of surgical site infection and compare it with our previous survey on surgical site infection prevention conducted in 2018. A questionnaire-based survey was conducted via the Internet among members of the Japanese Neurosurgical Society and the Japanese Society of Chemotherapy.

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Reconstruction of the anterior cruciate ligament (ACL) using hamstring autograft presents a greater risk of surgical site infection than other transplants (0.5% to 1.5%).

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Collateral Sensitivity to β-Lactam Antibiotics in Evolved Apramycin-Resistant MRSA.

Int J Mol Sci

November 2024

State Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou 510642, China.

Collateral sensitivity is an evolutionary trade-off for bacteria where acquiring resistance to one antibiotic results in an increased sensitivity to another antibiotic. This study was designed to evaluate the collateral sensitivity of methicillin-resistant (MRSA) to β-lactam antibiotics induced by the evolution of resistance to apramycin. Collateral sensitivity to ampicillin, cephazolin, ceftriaxone, cefotaxime, cefepime and cefquinome occurred after MRSA were exposed to apramycin and induced to acquire resistance.

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