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Fatal disseminated infection in a cat from Madrid, Spain.

JFMS Open Rep

January 2025

NEIKER-BRTA (Instituto Vasco de Investigación y Desarrollo Agrario - Basque Research and Technology Alliance), Derio, Bizkaia, Spain.

Case Summary: is a globally distributed apicomplexan protozoan infecting all warm-blooded animals. Cats are the definitive host, susceptible to clinical disease. In Spain, studies have shown the widespread presence of IgG antibodies in cats but there are no published data on clinical toxoplasmosis in cats from Spain.

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Background: Wound infections significantly impact morbidity, mortality, and healthcare costs globally. The Kashmir Valley's unique geographical and climatic conditions, coupled with resource constraints and antibiotic misuse, complicate managing these infections effectively. This study aimed to identify predominant bacterial pathogens in wound infections at a tertiary care hospital in Kashmir, determine their antibiotic susceptibility profiles, and estimate the prevalence of multidrug-resistant (MDR) strains.

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Background: Acne treatment can take weeks to deliver noticeable improvements, which may diminish patients' perception of treatment effectiveness and undermine treatment adherence. Combination topical treatments that target multiple acne pathophysiological pathways are more efficacious than topical monotherapies, and simplifying combination treatment by delivering multiple active ingredients as fixed combinations may improve adherence.

Methods: This review provides an overview of efficacy with 4 weeks of treatment in pivotal trials of fixed-combination topical treatments for acne.

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Corynebacterium species are an important cause of granulomatous mastitis (GM). Although there have been worldwide reports of infections caused by Corynebacterium kroppenstedtii, few cases of C. tuberculostearicum GM have been reported.

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Comparative clinical and incremental cost-effectiveness analysis of treatments for pelvic inflammatory disease in southern Brazil.

Int J Gynaecol Obstet

January 2025

Postgraduate Program in Medicine, Surgical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Objective: This paper evaluates the accuracy of C-reactive protein (CRP), leukocyte count, and neutrophil-to-lymphocyte ratio (NLR) for diagnosing tubo-ovarian abscess (TOA) and assessing the cost-effectiveness of different treatment regimens for pelvic inflammatory disease (PID), with and without TOA.

Method: A retrospective cohort study was conducted between January 1, 2003, and December 30, 2021, including women aged 13-80 years diagnosed with PID. The analysis focused on the incremental cost-effectiveness ratio of different treatment regimens.

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