AI Article Synopsis
- The study examined how secondary metabolites affect the growth of their producing organisms, specifically looking at nisin and enterotoxin B.
- When nisin was added to cultures of the nisin-producing strain of Streptococcus lactis, it showed significant inhibitory effects on both lag-phase and log-phase cells.
- In contrast, enterotoxin B added to Staphylococcus aureus strains did not show any inhibition of growth at any point, even at high concentrations.
Article Abstract
The effect of secondary metabolites added to cultures of the organisms producing them was investigated. Nisin was added to growing cultures of a nisin-producing strain of Streptococcus lactis (354/07) and enterotoxin B to strains of Staphylococcus aureus (S6 and 243) producing enterotoxin B. One quarter (12 mug/ml) of the amount of nisin formed by the culture of S. lactis inhibited lag-phase cells and lysed log-phase cells. The same amount of nisin added before inoculation or at a time when nisin synthesis had started (in late log phase), caused only transient delay in growth. Inhibition of growth of the two enterotoxin B-producing strains of S. aureus could not be demonstrated at any stage of their growth cycle with as much as 1 mg of enterotoxin B per ml of medium.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC444206 | PMC |
| http://dx.doi.org/10.1128/AAC.1.3.277 | DOI Listing |
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