Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Oligo-FISH barcode chromosome identification system provides novel insights into the natural chromosome aberrations propensity in the autotetraploid cultivated alfalfa.
Hortic Res
January 2025
Key Laboratory of Xinjiang Phytomedicine Resource and Utilization of Ministry of Education, Key Laboratory of Oasis Town and Mountain-basin System Ecology of Xinjiang Production and Construction Corps, College of Life Sciences, Shihezi University, Shihezi 832003, China.
Alfalfa is one of the most economically valuable forage crops in the world. However, molecular cytogenetic studies in alfalfa lag far behind other cash crops and have reached a bottleneck. Here, we developed a novel chromosome identification system by designing 21 oligo probes in specific regions of each chromosome, which can be used as a barcode to simultaneously distinguish all chromosomes in a cell.
View Article and Find Full Text PDFChromTR: chromosome detection in raw metaphase cell images via deformable transformers.
Front Med
December 2024
Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, Shanghai, 200240, China.
Chromosome karyotyping is a critical way to diagnose various hematological malignancies and genetic diseases, of which chromosome detection in raw metaphase cell images is the most critical and challenging step. In this work, focusing on the joint optimization of chromosome localization and classification, we propose ChromTR to accurately detect and classify 24 classes of chromosomes in raw metaphase cell images. ChromTR incorporates semantic feature learning and class distribution learning into a unified DETR-based detection framework.
View Article and Find Full Text PDFKaryotype, Male Meiosis, and Pollen Features of Barleria (Acanthaceae): A Wild Ornamental From India.
Microsc Microanal
November 2024
Angiosperm Taxonomy Laboratory, Department of Botany, Shivaji University, Kolhapur 416 004, Maharashtra, India.
Barleria is a palaeotropical genus of herbs, shrubs, and rarely climbers or trees. We investigated the karyotypes and male meiosis of 12 and 13 species, respectively, for the first time. Mitotic metaphases revealed two chromosome counts, 2n = 40 and 2n = 44.
View Article and Find Full Text PDFInvestigation of an MCM8 gene variant in women with premature ovarian insufficiency.
Einstein (Sao Paulo)
November 2024
Centro Universitário FMABC, Santo André, SP, Brazil.
Article Synopsis
- - The MCM8 gene is crucial for repairing DNA breaks and maintaining cell health, and its dysfunction can lead to cell death, especially in relation to primary ovarian insufficiency.
- - The study aimed to evaluate a specific variant of the MCM8 gene (NG_042869.1:g.40270G>A) in women with primary ovarian insufficiency by comparing samples from affected individuals to those from a control group.
- - Results showed the variant was present in one sample from the case group but absent in the control group, indicating it may be a rare, pathogenic variant associated with primary ovarian insufficiency in the studied population.
Turnover of retroelements and satellite DNA drives centromere reorganization over short evolutionary timescales in Drosophila.
PLoS Biol
November 2024
Department of Biology, University of Rochester, Rochester, New York, United States of America.
Centromeres reside in rapidly evolving, repeat-rich genomic regions, despite their essential function in chromosome segregation. Across organisms, centromeres are rich in selfish genetic elements such as transposable elements and satellite DNAs that can bias their transmission through meiosis. However, these elements still need to cooperate at some level and contribute to, or avoid interfering with, centromere function.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!