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Geospatial Analysis of Hymenolepis (Rodentolepis) nana Infection Transmission in Schools among Children in Cusco, Peru.
Am J Trop Med Hyg
March 2025
Division of Infectious Diseases, Department of Medicine, University of Texas Medical Branch, Galveston, Texas.
Hymenolepis nana is an emergent parasitosis, and the role of schools in infection transmission is unclear. Data from a cross-sectional study evaluating children for H. nana infection in schools in three districts of Anta province in Peru were analyzed.
View Article and Find Full Text PDFPathogenic Oligomeric Tau alters Neuronal RNA Processes through the Formation of Nuclear Heteromeric Amyloids with RNA-Binding Protein Musashi1.
Prog Neurobiol
March 2025
Mitchell Center for Neurodegenerative Diseases, The University of Texas Medical Branch, 301 University Blvd, Galveston, Texas 77555, USA; Departments of Neurology, The University of Texas Medical Branch, 301 University Blvd, Galveston, Texas 77555, USA. Electronic address:
Alzheimer's disease (AD) is marked by cytoplasmic proteinopathies, primarily involving misfolded Tau protein. Pathogenic Tau species, such as soluble oligomers and fibrils, disrupt RNA metabolism, though the mechanisms are unclear. Recent research indicates that RNA has a crucial role in Tau aggregation.
View Article and Find Full Text PDFCorticosteroid injection up to 8 weeks prior to ACL reconstruction doubles the incidence of post-operative infection.
Arthroscopy
March 2025
University of Texas Medical Branch, Department of Orthopaedic Surgery and Rehabilitation, 301 University Blvd., Galveston, TX; Shriners Children's Texas, 815 Market St., Galveston, TX 77550.
Purpose: This study was performed to determine if at least one corticosteroid injection (CSI) within 8-weeks prior to Anterior Cruciate Ligament Reconstruction (ACL-R) increases the incidence of postoperative infection.
Methods: A large globally federated research database (TriNetX) containing over 200 million patient records was retrospectively queried for patients undergoing ACL-R between October 1st, 2010, and January 1st, 2024 using diagnosis and procedure codes. A cohort of patients receiving CSI up to 8-weeks prior to ACL-R were compared to a cohort of patients who did not receive a CSI prior to ACL-R.
Contextual Determinants of Health Disparities in Utilization of Community-Based Rehabilitation Services Among Medicare Fee-for-Service Beneficiaries With Traumatic Brain Injury.
J Head Trauma Rehabil
March 2025
Author Affiliations: John Sealy School of Medicine (Mr Onwudebe and Ms Aguirre); Department of Population Health and Health Disparities (Ms Aguirre and Dr Pappadis), Department of Data Science and Biostatistics (Drs. Malagaris and Kuo), School of Public and Population Health; Sealy Center on Aging (Drs Kuo and Pappadis), University of Texas Medical Branch (UTMB), Galveston, Texas; and Brain Injury Research Center, TIRR Memorial Hermann (Dr. Pappadis), Houston, Texas.
Objective: To examine the association between contextual social determinants of health (SDoH) and receipt of first outpatient or home health (HH) rehabilitation visit after hospital discharge among older adults with traumatic brain injury (TBI) in Texas.
Setting: Community following hospital discharge.
Participants: 19 117 patients aged 66 and older hospitalized for a TBI from January 1, 2014, and discharged up to December 31, 2018, who returned home within 90 days from discharge.
Optimization of a panel of behavioral tests for use in containment using a golden Syrian hamster model.
J Virol Methods
March 2025
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, United States; World Reference Center for Emerging Viruses and Arboviruses, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX 77555, United States. Electronic address:
Golden Syrian hamsters are an often-overlooked model in behavioral testing. While previously utilized for research examining circadian rhythms and mammalian reproduction, they are less common than murine models in both infectious disease and behavioral studies. However, coronavirus disease-19 (COVID-19) quickly pushed hamster modeling to the forefront due to its myriad of advantages over mice in recapitulating human pathology and transmission.
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