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Mesenchymal stem cell therapy to promote limb transplant functional recovery.
Microsurgery
March 2017
Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, WA, 98431.
Background: Limb transplantation is a viable option for reconstruction after traumatic limb loss; however, functional recovery can be suboptimal. The aim of this study was to determine whether mesenchymal stem cell (MSC) administration can improve limb transplant functional recovery.
Methods: Orthotopic syngeneic hindlimb transplants were performed in Lewis rats, followed by topical and intravenous injections of syngeneic MSCs (5 × 10 ) or vehicle.
Lumbar spinal stenosis: analysis of pre- and postoperative somatosensory evoked potentials.
Arch Phys Med Rehabil
January 1985
Cortical somatosensory evoked potential (CSEP) examinations were performed of 20 patients with lumbar spinal stenosis a day prior to surgery and 10 to 12 days after spinal decompression and bilateral lateral fusion. CSEPs were recorded to Cz-Fz (10-20 international EEG system) following stimulation of 32 tibial, peroneal and sural nerves and 16 saphenous nerves. A total of 110 nerves were examined.
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